Effect of sodium ascorbate on bond strength and metalloproteinases activity in bleached dentin
Gláucia Cristina Rodrigues Nascimento,1 Mara Eliane Soares Ribeiro,1 Marcella Yasmin Reis Guerreiro,1 Eduardo Luís de Souza Cruz,2 João de Jesus Viana Pinheiro,2 Sandro Cordeiro Loretto11Dental Materials Laboratory of the Postgraduate Program in Dentistry, Institute...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2019-08-01
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| Series: | Clinical, Cosmetic and Investigational Dentistry |
| Subjects: | |
| Online Access: | https://www.dovepress.com/effect-of-sodium-ascorbate-on-bond-strength-and-metalloproteinases-act-peer-reviewed-article-CCIDE |
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| author | Nascimento GCR Ribeiro MES Guerreiro MYR Souza Cruz EL Pinheiro JJV Loretto SC |
| author_facet | Nascimento GCR Ribeiro MES Guerreiro MYR Souza Cruz EL Pinheiro JJV Loretto SC |
| author_sort | Nascimento GCR |
| collection | DOAJ |
| description | Gláucia Cristina Rodrigues Nascimento,1 Mara Eliane Soares Ribeiro,1 Marcella Yasmin Reis Guerreiro,1 Eduardo Luís de Souza Cruz,2 João de Jesus Viana Pinheiro,2 Sandro Cordeiro Loretto11Dental Materials Laboratory of the Postgraduate Program in Dentistry, Institute of Health Sciences, School of Dental, Federal University of Pará, Belém, Pará, Brazil; 2Department of Oral Pathology, School of Dental, Federal University of Pará, Belém, Pará, BrazilCorrespondence: Sandro Cordeiro LorettoDental Materials Laboratory of the Postgraduate Program in Dentistry, Institute of Health Sciences, School of Dental, Federal University of Pará, Avenue Conselheiro Furtado, Number 2312, Tower Oásis, Ap. 401, Cremação, Belém, Pará 66.040-100, BrazilTel +55 9 198 122 3477Email sandroloretto@hotmail.comAim: This study evaluated the effect of sodium ascorbate (SA) on the proteolytic activity of matrix metalloproteinases (MMPs) and investigated the related effects on the bond strength of bleached dentin.Materials and methods: Eighty freshly extracted human third molars were randomly divided according to treatment (bleaching or SA application), type of analysis (microshear or measuring MMP activity), and post-bleaching time to assess bond strength (24 hrs or 30 days). Data from both analyses were subjected to one-way analysis of variance to detect differences among groups, followed by Tukey’s multiple comparison test (p≤0.05).Results: Dental bleaching significantly reduced bond strength values when the adhesive strategy was performed after 24 hrs (despite the SA treatment) or 30 days after the bleaching procedure. However, after 30 days, the bond strength values of the groups who received bleaching or SA application were similar to those of the unbleached group. Dental bleaching caused the activation of MMPs, and SA did not influence this activity.Conclusion: It was concluded that SA does not affect the activity of MMPs or the bond strength in bleached dentin immediately after the bleaching treatment.Keywords: tooth bleaching, antioxidants, bleaching agents, dental bonding |
| first_indexed | 2024-12-12T01:46:33Z |
| format | Article |
| id | doaj.art-3e4a2eac659842cd813cbd23a7118fd7 |
| institution | Directory Open Access Journal |
| issn | 1179-1357 |
| language | English |
| last_indexed | 2024-12-12T01:46:33Z |
| publishDate | 2019-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical, Cosmetic and Investigational Dentistry |
| spelling | doaj.art-3e4a2eac659842cd813cbd23a7118fd72022-12-22T00:42:34ZengDove Medical PressClinical, Cosmetic and Investigational Dentistry1179-13572019-08-01Volume 1125926547967Effect of sodium ascorbate on bond strength and metalloproteinases activity in bleached dentinNascimento GCRRibeiro MESGuerreiro MYRSouza Cruz ELPinheiro JJVLoretto SCGláucia Cristina Rodrigues Nascimento,1 Mara Eliane Soares Ribeiro,1 Marcella Yasmin Reis Guerreiro,1 Eduardo Luís de Souza Cruz,2 João de Jesus Viana Pinheiro,2 Sandro Cordeiro Loretto11Dental Materials Laboratory of the Postgraduate Program in Dentistry, Institute of Health Sciences, School of Dental, Federal University of Pará, Belém, Pará, Brazil; 2Department of Oral Pathology, School of Dental, Federal University of Pará, Belém, Pará, BrazilCorrespondence: Sandro Cordeiro LorettoDental Materials Laboratory of the Postgraduate Program in Dentistry, Institute of Health Sciences, School of Dental, Federal University of Pará, Avenue Conselheiro Furtado, Number 2312, Tower Oásis, Ap. 401, Cremação, Belém, Pará 66.040-100, BrazilTel +55 9 198 122 3477Email sandroloretto@hotmail.comAim: This study evaluated the effect of sodium ascorbate (SA) on the proteolytic activity of matrix metalloproteinases (MMPs) and investigated the related effects on the bond strength of bleached dentin.Materials and methods: Eighty freshly extracted human third molars were randomly divided according to treatment (bleaching or SA application), type of analysis (microshear or measuring MMP activity), and post-bleaching time to assess bond strength (24 hrs or 30 days). Data from both analyses were subjected to one-way analysis of variance to detect differences among groups, followed by Tukey’s multiple comparison test (p≤0.05).Results: Dental bleaching significantly reduced bond strength values when the adhesive strategy was performed after 24 hrs (despite the SA treatment) or 30 days after the bleaching procedure. However, after 30 days, the bond strength values of the groups who received bleaching or SA application were similar to those of the unbleached group. Dental bleaching caused the activation of MMPs, and SA did not influence this activity.Conclusion: It was concluded that SA does not affect the activity of MMPs or the bond strength in bleached dentin immediately after the bleaching treatment.Keywords: tooth bleaching, antioxidants, bleaching agents, dental bondinghttps://www.dovepress.com/effect-of-sodium-ascorbate-on-bond-strength-and-metalloproteinases-act-peer-reviewed-article-CCIDEtooth bleachingantioxidantsbleaching agentsdental bonding |
| spellingShingle | Nascimento GCR Ribeiro MES Guerreiro MYR Souza Cruz EL Pinheiro JJV Loretto SC Effect of sodium ascorbate on bond strength and metalloproteinases activity in bleached dentin Clinical, Cosmetic and Investigational Dentistry tooth bleaching antioxidants bleaching agents dental bonding |
| title | Effect of sodium ascorbate on bond strength and metalloproteinases activity in bleached dentin |
| title_full | Effect of sodium ascorbate on bond strength and metalloproteinases activity in bleached dentin |
| title_fullStr | Effect of sodium ascorbate on bond strength and metalloproteinases activity in bleached dentin |
| title_full_unstemmed | Effect of sodium ascorbate on bond strength and metalloproteinases activity in bleached dentin |
| title_short | Effect of sodium ascorbate on bond strength and metalloproteinases activity in bleached dentin |
| title_sort | effect of sodium ascorbate on bond strength and metalloproteinases activity in bleached dentin |
| topic | tooth bleaching antioxidants bleaching agents dental bonding |
| url | https://www.dovepress.com/effect-of-sodium-ascorbate-on-bond-strength-and-metalloproteinases-act-peer-reviewed-article-CCIDE |
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