Seroepidemiological Study of Visceral Leishmaniasis (Kala-azar) in Ardabil Province, Iran, 1986 – 2009

Introduction & Objective: Visceral Leishmaniasis (kala-azar) is the most important endemic disease in Northwestern Iran, particularly in Ardabil province. This study aimed to review the seroepidemiological studies which have been performed in Ardabil province during 1986-2009. Materials &...

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Main Authors: S Molaie, M Mohebali, A Gangi, F Pourfarzi, D Emdadi, N Modarres - sadrani, M Nasiri, Gh Soleimanzadeh, M Farajzadeh, Z Zarei
Format: Article
Language:fas
Published: Yasuj University Of Medical Sciences 2010-10-01
Series:Armaghane Danesh Bimonthly Journal
Subjects:
Online Access:http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-337&slc_lang=en&sid=1
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author S Molaie
M Mohebali
A Gangi
F Pourfarzi
D Emdadi
N Modarres - sadrani
M Nasiri
Gh Soleimanzadeh
M Farajzadeh
Z Zarei
author_facet S Molaie
M Mohebali
A Gangi
F Pourfarzi
D Emdadi
N Modarres - sadrani
M Nasiri
Gh Soleimanzadeh
M Farajzadeh
Z Zarei
author_sort S Molaie
collection DOAJ
description Introduction & Objective: Visceral Leishmaniasis (kala-azar) is the most important endemic disease in Northwestern Iran, particularly in Ardabil province. This study aimed to review the seroepidemiological studies which have been performed in Ardabil province during 1986-2009. Materials & Methods: In this descriptive analytical study, studies which have been carried out from 1986 through 2009 in Northwestern Iran about clinical, diagnostic and epidemiological features of Kala azar, using DAT, were reviewed. Collected data were analyzed using the SPSS software. Results: in total, 2703 of human visceral leishmaniasis were detected by direct agglutination test (DAT) in Ardabil province, 1787 (66.1%) of them were from Meshkin-shahr district, 837 (31%) cases were from Moghan district, and 79 (2.9%) cases were from Ardabil district. Ninety eight percent of the cases were under 10 years old while only 0.5% of the VL cases were ≥20 years old and 17% of them were under 1 year of age. Conclusion: Currently Kala-Azar is the most important endemic disease in Northwestern Iran, particularly in Ardabil province. Anti-Leishmania antibodies at the titers of ≥1:3200 using DAT along with clinical signs including fever, anemia and hepatosplenomegaly are considered as active visceral leishmaniasis. DAT antibody titer of 1/800 and lower and absent of clinical signs is considered as negative VL.
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spelling doaj.art-3e4ab5aa2d204350a16410d0799d446b2022-12-22T02:02:04ZfasYasuj University Of Medical SciencesArmaghane Danesh Bimonthly Journal1728-65061728-65142010-10-01153262272Seroepidemiological Study of Visceral Leishmaniasis (Kala-azar) in Ardabil Province, Iran, 1986 – 2009S Molaie0M Mohebali1A Gangi2F Pourfarzi3D Emdadi4N Modarres - sadrani5M Nasiri6Gh Soleimanzadeh7M Farajzadeh8Z Zarei9 Introduction & Objective: Visceral Leishmaniasis (kala-azar) is the most important endemic disease in Northwestern Iran, particularly in Ardabil province. This study aimed to review the seroepidemiological studies which have been performed in Ardabil province during 1986-2009. Materials & Methods: In this descriptive analytical study, studies which have been carried out from 1986 through 2009 in Northwestern Iran about clinical, diagnostic and epidemiological features of Kala azar, using DAT, were reviewed. Collected data were analyzed using the SPSS software. Results: in total, 2703 of human visceral leishmaniasis were detected by direct agglutination test (DAT) in Ardabil province, 1787 (66.1%) of them were from Meshkin-shahr district, 837 (31%) cases were from Moghan district, and 79 (2.9%) cases were from Ardabil district. Ninety eight percent of the cases were under 10 years old while only 0.5% of the VL cases were ≥20 years old and 17% of them were under 1 year of age. Conclusion: Currently Kala-Azar is the most important endemic disease in Northwestern Iran, particularly in Ardabil province. Anti-Leishmania antibodies at the titers of ≥1:3200 using DAT along with clinical signs including fever, anemia and hepatosplenomegaly are considered as active visceral leishmaniasis. DAT antibody titer of 1/800 and lower and absent of clinical signs is considered as negative VL.http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-337&slc_lang=en&sid=1Visceral Leishmaniasis (kala-azar) seroepidemiology Human
spellingShingle S Molaie
M Mohebali
A Gangi
F Pourfarzi
D Emdadi
N Modarres - sadrani
M Nasiri
Gh Soleimanzadeh
M Farajzadeh
Z Zarei
Seroepidemiological Study of Visceral Leishmaniasis (Kala-azar) in Ardabil Province, Iran, 1986 – 2009
Armaghane Danesh Bimonthly Journal
Visceral Leishmaniasis (kala-azar)
seroepidemiology
Human
title Seroepidemiological Study of Visceral Leishmaniasis (Kala-azar) in Ardabil Province, Iran, 1986 – 2009
title_full Seroepidemiological Study of Visceral Leishmaniasis (Kala-azar) in Ardabil Province, Iran, 1986 – 2009
title_fullStr Seroepidemiological Study of Visceral Leishmaniasis (Kala-azar) in Ardabil Province, Iran, 1986 – 2009
title_full_unstemmed Seroepidemiological Study of Visceral Leishmaniasis (Kala-azar) in Ardabil Province, Iran, 1986 – 2009
title_short Seroepidemiological Study of Visceral Leishmaniasis (Kala-azar) in Ardabil Province, Iran, 1986 – 2009
title_sort seroepidemiological study of visceral leishmaniasis kala azar in ardabil province iran 1986 2009
topic Visceral Leishmaniasis (kala-azar)
seroepidemiology
Human
url http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-337&slc_lang=en&sid=1
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