Simultaneous determination of pioglitazone and candesartan in human plasma by LC-MS/MS and its application to a human pharmacokinetic study

Simultaneous determination of pioglitazone and candesartan in human plasma by LC-MS/MS and its application to a human pharmacokinetic study

A simple and rapid liquid chromatography-tandem mass spectrometric (LC-MS/MS) assay method has been developed and fully validated for simultaneous quantification of pioglitazone and candesartan in human plasma. Irbesartan was used as an internal standard. The analytes were extracted from human plasm...

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Bibliographic Details
Main Authors:	Vijaya Kumari Karra, Nageswara Rao Pilli, Jaswanth Kumar Inamadugu, J.V.L.N. Seshagiri Rao
Format:	Article
Language:	English
Published:	Elsevier 2012-06-01
Series:	Journal of Pharmaceutical Analysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095177912000123

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