Immune checkpoints on T and NK cells in the context of HBV infection: Landscape, pathophysiology and therapeutic exploitation

Immune checkpoints on T and NK cells in the context of HBV infection: Landscape, pathophysiology and therapeutic exploitation

In hepatitis B virus (HBV) infection, the interplay between the virus and the host immune system is crucial in determining the pathogenesis of the disease. Patients who fail to mount a sufficient and sustained anti-viral immune response develop chronic hepatitis B (CHB). T cells and natural killer (...

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Bibliographic Details
Main Authors: Lucile Dumolard, Caroline Aspord, Patrice N. Marche, Zuzana Macek Jilkova
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
HBV
T cells
NK cells
immune checkpoint molecules
anti-viral activity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1148111/full

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