Structural basis of cooperativity in human UDP-glucose dehydrogenase.

Structural basis of cooperativity in human UDP-glucose dehydrogenase.

BACKGROUND: UDP-glucose dehydrogenase (UGDH) is the sole enzyme that catalyzes the conversion of UDP-glucose to UDP-glucuronic acid. The product is used in xenobiotic glucuronidation in hepatocytes and in the production of proteoglycans that are involved in promoting normal cellular growth and migra...

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Main Authors: Venkatachalam Rajakannan, Hui-Sun Lee, Seon-Ha Chong, Han-Bong Ryu, Ji-Young Bae, Eun-Young Whang, Jae-Wan Huh, Sung-Woo Cho, Lin-Woo Kang, Han Choe, Robert C Robinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3184952?pdf=render

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http://europepmc.org/articles/PMC3184952?pdf=render

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