Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1

Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1

The non-structural protein NS1 of influenza A viruses is an RNA-binding protein of which its activities in the infected cell contribute to the success of the viral cycle, notably through interferon antagonism. We have previously shown that NS1 strongly binds RNA aptamers harbouring virus-specific se...

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Bibliographic Details
Main Authors: Alan Wacquiez, Franck Coste, Emmanuel Kut, Virginie Gaudon, Sascha Trapp, Bertrand Castaing, Daniel Marc
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Viruses
Subjects:
influenza A virus
non-structural NS1
RNA
RNA-protein interaction
3D structure
Online Access:https://www.mdpi.com/1999-4915/12/9/947

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