Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study
Introduction: Gynecological malignancies include malignancies affecting the female reproductive organs ovary, cervix, body of uterus, vulva, vagina, and gestational trophoblastic neoplasia. Materials and Methods: This is a hospital-based retrospective observational study of histopathological confi...
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Format: | Article |
Language: | English |
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HEAD Nepal
2021-06-01
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Series: | Nepalese Medical Journal |
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Online Access: | https://www.nepjol.info/index.php/nmj/article/view/37717 |
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author | Bishal Khaniya |
author_facet | Bishal Khaniya |
author_sort | Bishal Khaniya |
collection | DOAJ |
description | Introduction: Gynecological malignancies include malignancies affecting the female reproductive organs ovary, cervix, body of uterus, vulva, vagina, and gestational trophoblastic neoplasia.
Materials and Methods: This is a hospital-based retrospective observational study of histopathological confirmed gynecological malignancies conducted in the department of Obstetrics and Gynecology, TUTH, Maharajgunj, Kathmandu for 3 years from April 2016 to March 2018.
Results: Among 314 cases enrolled in the study, the most common gynecological malignancy was of ovary (50.63%), followed by the cervix (30.25%), endometrium (9.23%), (4.77%) gestational trophoblastic neoplasia (3.82%), and fallopian tube (1.27%). 71% of the gynecological malignancies presented in early-stage and 29% in late-stage. The most common histopathological diagnosis of ovarian cancer was serous cystadenocarcinoma (30.18%), cervical cancer was squamous cell non-keratinizing type (46.3%), endometrial carcinoma was endometrioid adenocarcinoma (55%), vulval carcinoma was squamous cell carcinoma (86%), fallopian tube carcinoma (100%). The mean age of gynecological malignancy was 49.06 +- 10.08 years.
Conclusions: Screening of gynecological malignancy is necessary to identify the disease in early-stage to decrease maternal morbidity and mortality. |
first_indexed | 2024-12-16T14:07:03Z |
format | Article |
id | doaj.art-3e5480f7e8724c6cb9a3ce5cf80c9c1a |
institution | Directory Open Access Journal |
issn | 2631-2093 2645-8586 |
language | English |
last_indexed | 2024-12-16T14:07:03Z |
publishDate | 2021-06-01 |
publisher | HEAD Nepal |
record_format | Article |
series | Nepalese Medical Journal |
spelling | doaj.art-3e5480f7e8724c6cb9a3ce5cf80c9c1a2022-12-21T22:28:54ZengHEAD NepalNepalese Medical Journal2631-20932645-85862021-06-014144244510.3126/nmj.v4i1.3771734504Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years StudyBishal Khaniya0https://orcid.org/0000-0002-7191-0955Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, NepalIntroduction: Gynecological malignancies include malignancies affecting the female reproductive organs ovary, cervix, body of uterus, vulva, vagina, and gestational trophoblastic neoplasia. Materials and Methods: This is a hospital-based retrospective observational study of histopathological confirmed gynecological malignancies conducted in the department of Obstetrics and Gynecology, TUTH, Maharajgunj, Kathmandu for 3 years from April 2016 to March 2018. Results: Among 314 cases enrolled in the study, the most common gynecological malignancy was of ovary (50.63%), followed by the cervix (30.25%), endometrium (9.23%), (4.77%) gestational trophoblastic neoplasia (3.82%), and fallopian tube (1.27%). 71% of the gynecological malignancies presented in early-stage and 29% in late-stage. The most common histopathological diagnosis of ovarian cancer was serous cystadenocarcinoma (30.18%), cervical cancer was squamous cell non-keratinizing type (46.3%), endometrial carcinoma was endometrioid adenocarcinoma (55%), vulval carcinoma was squamous cell carcinoma (86%), fallopian tube carcinoma (100%). The mean age of gynecological malignancy was 49.06 +- 10.08 years. Conclusions: Screening of gynecological malignancy is necessary to identify the disease in early-stage to decrease maternal morbidity and mortality.https://www.nepjol.info/index.php/nmj/article/view/37717endometrioid; gynecological malignancy; ovarian cancer; squamous cell carcinoma |
spellingShingle | Bishal Khaniya Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study Nepalese Medical Journal endometrioid; gynecological malignancy; ovarian cancer; squamous cell carcinoma |
title | Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study |
title_full | Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study |
title_fullStr | Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study |
title_full_unstemmed | Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study |
title_short | Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study |
title_sort | histopathological pattern of gynecological malignancies at tribhuvan university teaching hospital nepal a 3 years study |
topic | endometrioid; gynecological malignancy; ovarian cancer; squamous cell carcinoma |
url | https://www.nepjol.info/index.php/nmj/article/view/37717 |
work_keys_str_mv | AT bishalkhaniya histopathologicalpatternofgynecologicalmalignanciesattribhuvanuniversityteachinghospitalnepala3yearsstudy |