Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature

Congestive heart failure (HF) remains a major cause of cardiac-related morbidity and mortality, despite major therapeutic advancements. A newer class of medications has recently been developed which targets the root cause of HF, which is reduced myocardial contractility. This article aims to highlig...

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Bibliographic Details
Main Authors: Arroj Ali, Ramy Abdelmaseih, Ravi Thakker, Mohammed Faluk, Syed Mustajab Hasan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Heart Views
Subjects:
Online Access:http://www.heartviews.org/article.asp?issn=1995-705X;year=2021;volume=22;issue=4;spage=275;epage=279;aulast=Ali
Description
Summary:Congestive heart failure (HF) remains a major cause of cardiac-related morbidity and mortality, despite major therapeutic advancements. A newer class of medications has recently been developed which targets the root cause of HF, which is reduced myocardial contractility. This article aims to highlight the cardiac myosin activator class of drugs and the trials to date highlighting their effects on HF outcomes.
ISSN:1995-705X