Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature
Congestive heart failure (HF) remains a major cause of cardiac-related morbidity and mortality, despite major therapeutic advancements. A newer class of medications has recently been developed which targets the root cause of HF, which is reduced myocardial contractility. This article aims to highlig...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2021-01-01
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Series: | Heart Views |
Subjects: | |
Online Access: | http://www.heartviews.org/article.asp?issn=1995-705X;year=2021;volume=22;issue=4;spage=275;epage=279;aulast=Ali |
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author | Arroj Ali Ramy Abdelmaseih Ravi Thakker Mohammed Faluk Syed Mustajab Hasan |
author_facet | Arroj Ali Ramy Abdelmaseih Ravi Thakker Mohammed Faluk Syed Mustajab Hasan |
author_sort | Arroj Ali |
collection | DOAJ |
description | Congestive heart failure (HF) remains a major cause of cardiac-related morbidity and mortality, despite major therapeutic advancements. A newer class of medications has recently been developed which targets the root cause of HF, which is reduced myocardial contractility. This article aims to highlight the cardiac myosin activator class of drugs and the trials to date highlighting their effects on HF outcomes. |
first_indexed | 2024-12-10T17:04:55Z |
format | Article |
id | doaj.art-3e5885a6c109401e9a4c8bfcc72e2926 |
institution | Directory Open Access Journal |
issn | 1995-705X |
language | English |
last_indexed | 2024-12-10T17:04:55Z |
publishDate | 2021-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Heart Views |
spelling | doaj.art-3e5885a6c109401e9a4c8bfcc72e29262022-12-22T01:40:29ZengWolters Kluwer Medknow PublicationsHeart Views1995-705X2021-01-0122427527910.4103/HEARTVIEWS.HEARTVIEWS_39_21Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literatureArroj AliRamy AbdelmaseihRavi ThakkerMohammed FalukSyed Mustajab HasanCongestive heart failure (HF) remains a major cause of cardiac-related morbidity and mortality, despite major therapeutic advancements. A newer class of medications has recently been developed which targets the root cause of HF, which is reduced myocardial contractility. This article aims to highlight the cardiac myosin activator class of drugs and the trials to date highlighting their effects on HF outcomes.http://www.heartviews.org/article.asp?issn=1995-705X;year=2021;volume=22;issue=4;spage=275;epage=279;aulast=Aliheart failuremyosinomecamtiv mecarbil |
spellingShingle | Arroj Ali Ramy Abdelmaseih Ravi Thakker Mohammed Faluk Syed Mustajab Hasan Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature Heart Views heart failure myosin omecamtiv mecarbil |
title | Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature |
title_full | Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature |
title_fullStr | Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature |
title_full_unstemmed | Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature |
title_short | Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature |
title_sort | cardiac myosin activation in the treatment of congestive heart failure new therapeutic options and review of literature |
topic | heart failure myosin omecamtiv mecarbil |
url | http://www.heartviews.org/article.asp?issn=1995-705X;year=2021;volume=22;issue=4;spage=275;epage=279;aulast=Ali |
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