Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature

Congestive heart failure (HF) remains a major cause of cardiac-related morbidity and mortality, despite major therapeutic advancements. A newer class of medications has recently been developed which targets the root cause of HF, which is reduced myocardial contractility. This article aims to highlig...

Full description

Bibliographic Details
Main Authors: Arroj Ali, Ramy Abdelmaseih, Ravi Thakker, Mohammed Faluk, Syed Mustajab Hasan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Heart Views
Subjects:
Online Access:http://www.heartviews.org/article.asp?issn=1995-705X;year=2021;volume=22;issue=4;spage=275;epage=279;aulast=Ali
_version_ 1818489509690474496
author Arroj Ali
Ramy Abdelmaseih
Ravi Thakker
Mohammed Faluk
Syed Mustajab Hasan
author_facet Arroj Ali
Ramy Abdelmaseih
Ravi Thakker
Mohammed Faluk
Syed Mustajab Hasan
author_sort Arroj Ali
collection DOAJ
description Congestive heart failure (HF) remains a major cause of cardiac-related morbidity and mortality, despite major therapeutic advancements. A newer class of medications has recently been developed which targets the root cause of HF, which is reduced myocardial contractility. This article aims to highlight the cardiac myosin activator class of drugs and the trials to date highlighting their effects on HF outcomes.
first_indexed 2024-12-10T17:04:55Z
format Article
id doaj.art-3e5885a6c109401e9a4c8bfcc72e2926
institution Directory Open Access Journal
issn 1995-705X
language English
last_indexed 2024-12-10T17:04:55Z
publishDate 2021-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Heart Views
spelling doaj.art-3e5885a6c109401e9a4c8bfcc72e29262022-12-22T01:40:29ZengWolters Kluwer Medknow PublicationsHeart Views1995-705X2021-01-0122427527910.4103/HEARTVIEWS.HEARTVIEWS_39_21Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literatureArroj AliRamy AbdelmaseihRavi ThakkerMohammed FalukSyed Mustajab HasanCongestive heart failure (HF) remains a major cause of cardiac-related morbidity and mortality, despite major therapeutic advancements. A newer class of medications has recently been developed which targets the root cause of HF, which is reduced myocardial contractility. This article aims to highlight the cardiac myosin activator class of drugs and the trials to date highlighting their effects on HF outcomes.http://www.heartviews.org/article.asp?issn=1995-705X;year=2021;volume=22;issue=4;spage=275;epage=279;aulast=Aliheart failuremyosinomecamtiv mecarbil
spellingShingle Arroj Ali
Ramy Abdelmaseih
Ravi Thakker
Mohammed Faluk
Syed Mustajab Hasan
Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature
Heart Views
heart failure
myosin
omecamtiv mecarbil
title Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature
title_full Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature
title_fullStr Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature
title_full_unstemmed Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature
title_short Cardiac myosin activation in the treatment of congestive heart failure: New therapeutic options and review of literature
title_sort cardiac myosin activation in the treatment of congestive heart failure new therapeutic options and review of literature
topic heart failure
myosin
omecamtiv mecarbil
url http://www.heartviews.org/article.asp?issn=1995-705X;year=2021;volume=22;issue=4;spage=275;epage=279;aulast=Ali
work_keys_str_mv AT arrojali cardiacmyosinactivationinthetreatmentofcongestiveheartfailurenewtherapeuticoptionsandreviewofliterature
AT ramyabdelmaseih cardiacmyosinactivationinthetreatmentofcongestiveheartfailurenewtherapeuticoptionsandreviewofliterature
AT ravithakker cardiacmyosinactivationinthetreatmentofcongestiveheartfailurenewtherapeuticoptionsandreviewofliterature
AT mohammedfaluk cardiacmyosinactivationinthetreatmentofcongestiveheartfailurenewtherapeuticoptionsandreviewofliterature
AT syedmustajabhasan cardiacmyosinactivationinthetreatmentofcongestiveheartfailurenewtherapeuticoptionsandreviewofliterature