Quantitative live imaging of endogenous DNA replication in mammalian cells.

Quantitative live imaging of endogenous DNA replication in mammalian cells.

Historically, the analysis of DNA replication in mammalian tissue culture cells has been limited to static time points, and the use of nucleoside analogues to pulse-label replicating DNA. Here we characterize for the first time a novel Chromobody cell line that specifically labels endogenous PCNA. B...

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Bibliographic Details
Main Authors:	Andrew Burgess, Thierry Lorca, Anna Castro
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3447815?pdf=render

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