Phosphoregulation of the yeast Pma1 H+-ATPase autoinhibitory domain involves the Ptk1/2 kinases and the Glc7 PP1 phosphatase and is under TORC1 control.
Plasma membrane (PM) H+-ATPases of the P-type family are highly conserved in yeast, other fungi, and plants. Their main role is to establish an H+ gradient driving active transport of small ions and metabolites across the PM and providing the main component of the PM potential. Furthermore, in both...
Main Authors: | Nadia Guarini, Elie Saliba, Bruno André |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2024-01-01
|
Series: | PLoS Genetics |
Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011121&type=printable |
Similar Items
-
The yeast H+-ATPase Pma1 promotes Rag/Gtr-dependent TORC1 activation in response to H+-coupled nutrient uptake
by: Elie Saliba, et al.
Published: (2018-03-01) -
Two inhibitors of yeast plasma membrane ATPase 1 (ScPma1p): toward the development of novel antifungal therapies
by: Sabine Ottilie, et al.
Published: (2018-02-01) -
Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8
by: Lukas M Langer, et al.
Published: (2021-10-01) -
The Mitogen-Activated Protein Kinase Slt2 Promotes Asymmetric Cell Cycle Arrest and Reduces TORC1-Sch9 Signaling in Yeast Lacking the Protein Phosphatase Ptc1
by: Gema González-Rubio, et al.
Published: (2023-06-01) -
<i>Fusarium oxysporum</i> Casein Kinase 1, a Negative Regulator of the Plasma Membrane H<sup>+</sup>-ATPase Pma1, Is Required for Development and Pathogenicity
by: Melani Mariscal, et al.
Published: (2022-12-01)