Nucleopore Traffic Is Hindered by SARS-CoV-2 ORF6 Protein to Efficiently Suppress IFN-β and IL-6 Secretion

Nucleopore Traffic Is Hindered by SARS-CoV-2 ORF6 Protein to Efficiently Suppress IFN-β and IL-6 Secretion

A weak production of INF-β along with an exacerbated release of pro-inflammatory cytokines have been reported during infection by the novel SARS-CoV-2 virus. SARS-CoV-2 encodes several proteins that are able to counteract the host immune system, which is believed to be one of the most important feat...

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Bibliographic Details
Main Authors: Gianni Gori Savellini, Gabriele Anichini, Claudia Gandolfo, Maria Grazia Cusi
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
interleukin-6
SARS-CoV-2 ORF6 protein
interferon antagonist
Online Access:https://www.mdpi.com/1999-4915/14/6/1273

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