Herbicide and Cytogenotoxic Activity of Inclusion Complexes of <i>Psidium gaudichaudianum</i> Leaf Essential Oil and <i>β</i>-Caryophyllene on 2-Hydroxypropyl-<i>β</i>-cyclodextrin
The present investigation aimed to develop inclusion complexes (ICs) from <i>Psidium gaudichaudianum</i> (GAU) essential oil (EO) and its major compound <i>β</i>-caryophyllene (<i>β</i>-CAR), and to evaluate their herbicidal (against <i>Lolium multiflorum<...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/15/5909 |
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| author | Luiza Alves Mendes Loren Cristina Vasconcelos Milene Miranda Praça Fontes Geisiele Silva Martins Aline dos Santos Bergamin Matheus Alves Silva Rafael Resende Assis Silva Taíla Veloso de Oliveira Victor Gomes Lauriano Souza Marcia Flores da Silva Ferreira Róbson Ricardo Teixeira Renata Pereira Lopes |
| author_facet | Luiza Alves Mendes Loren Cristina Vasconcelos Milene Miranda Praça Fontes Geisiele Silva Martins Aline dos Santos Bergamin Matheus Alves Silva Rafael Resende Assis Silva Taíla Veloso de Oliveira Victor Gomes Lauriano Souza Marcia Flores da Silva Ferreira Róbson Ricardo Teixeira Renata Pereira Lopes |
| author_sort | Luiza Alves Mendes |
| collection | DOAJ |
| description | The present investigation aimed to develop inclusion complexes (ICs) from <i>Psidium gaudichaudianum</i> (GAU) essential oil (EO) and its major compound <i>β</i>-caryophyllene (<i>β</i>-CAR), and to evaluate their herbicidal (against <i>Lolium multiflorum</i> and <i>Bidens pilosa</i>) and cytogenotoxic (on <i>Lactuca sativa</i>) activities. The ICs were obtained using 2-hydroxypropyl-<i>β</i>-cyclodextrin (HP<i>β</i>CD) and they were prepared to avoid or reduce the volatility and degradation of GAU EO and <i>β</i>-CAR. The ICs obtained showed a complexation efficiency of 91.5 and 83.9% for GAU EO and <i>β</i>-CAR, respectively. The IC of GAU EO at a concentration of 3000 µg mL<sup>−1</sup> displayed a significant effect against weed species <i>B. pilosa</i> and <i>L. multiflorum</i>. However, the <i>β</i>-CAR IC at a concentration of 3000 µg mL<sup>−1</sup> was effective only on <i>L. multiflorum</i>. In addition, the cytogenotoxic activity evaluation revealed that there was a reduction in the mitotic index and an increase in chromosomal abnormalities. The produced ICs were able to protect the EO and <i>β</i>-CAR from volatility and degradation, with a high thermal stability, and they also enabled the solubilization of the EO and <i>β</i>-CAR in water without the addition of an organic solvent. Therefore, it is possible to indicate the obtained products as potential candidates for commercial exploration since the ICs allow the complexed EO to exhibit a more stable chemical constitution than pure EO under storage conditions. |
| first_indexed | 2024-03-11T00:20:21Z |
| format | Article |
| id | doaj.art-3e70cec3a4bf4096a92ad42953ed3744 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T00:20:21Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-3e70cec3a4bf4096a92ad42953ed37442023-11-18T23:20:29ZengMDPI AGMolecules1420-30492023-08-012815590910.3390/molecules28155909Herbicide and Cytogenotoxic Activity of Inclusion Complexes of <i>Psidium gaudichaudianum</i> Leaf Essential Oil and <i>β</i>-Caryophyllene on 2-Hydroxypropyl-<i>β</i>-cyclodextrinLuiza Alves Mendes0Loren Cristina Vasconcelos1Milene Miranda Praça Fontes2Geisiele Silva Martins3Aline dos Santos Bergamin4Matheus Alves Silva5Rafael Resende Assis Silva6Taíla Veloso de Oliveira7Victor Gomes Lauriano Souza8Marcia Flores da Silva Ferreira9Róbson Ricardo Teixeira10Renata Pereira Lopes11Departament of Chemistry, Federal University of Viçosa (UFV), Av. Peter Henry Rolfs, s/n, Campus Universitário, Viçosa 36570-000, MG, BrazilDepartment of Biology, Federal University of Espírito Santo (UFES), Alto Universitário, s/n, Guararema, Alegre 29500-000, ES, BrazilDepartment of Biology, Federal University of Espírito Santo (UFES), Alto Universitário, s/n, Guararema, Alegre 29500-000, ES, BrazilDepartment of Biology, Federal University of Espírito Santo (UFES), Alto Universitário, s/n, Guararema, Alegre 29500-000, ES, BrazilDepartment of Agronomy, Federal University of Espírito Santo (UFES), Alto Universitário, s/n, Guararema, Alegre 29500-000, ES, BrazilDepartment of Agronomy, Federal University of Espírito Santo (UFES), Alto Universitário, s/n, Guararema, Alegre 29500-000, ES, BrazilDepartament of Food Materials Science and Engineering, Federal University of São Carlos (UFSCar), Rod. Washington Luiz, s/n, São Carlos 13565-905, SP, BrazilDepartment of Food Technology, Federal University of Viçosa, Viçosa 36570-900, MG, BrazilInternational Iberian Nanotechnology Laboratory (INL), Av. Mestre José Veiga s/n, 4715-330 Braga, PortugalDepartment of Agronomy, Federal University of Espírito Santo (UFES), Alto Universitário, s/n, Guararema, Alegre 29500-000, ES, BrazilDepartament of Chemistry, Federal University of Viçosa (UFV), Av. Peter Henry Rolfs, s/n, Campus Universitário, Viçosa 36570-000, MG, BrazilDepartament of Chemistry, Federal University of Viçosa (UFV), Av. Peter Henry Rolfs, s/n, Campus Universitário, Viçosa 36570-000, MG, BrazilThe present investigation aimed to develop inclusion complexes (ICs) from <i>Psidium gaudichaudianum</i> (GAU) essential oil (EO) and its major compound <i>β</i>-caryophyllene (<i>β</i>-CAR), and to evaluate their herbicidal (against <i>Lolium multiflorum</i> and <i>Bidens pilosa</i>) and cytogenotoxic (on <i>Lactuca sativa</i>) activities. The ICs were obtained using 2-hydroxypropyl-<i>β</i>-cyclodextrin (HP<i>β</i>CD) and they were prepared to avoid or reduce the volatility and degradation of GAU EO and <i>β</i>-CAR. The ICs obtained showed a complexation efficiency of 91.5 and 83.9% for GAU EO and <i>β</i>-CAR, respectively. The IC of GAU EO at a concentration of 3000 µg mL<sup>−1</sup> displayed a significant effect against weed species <i>B. pilosa</i> and <i>L. multiflorum</i>. However, the <i>β</i>-CAR IC at a concentration of 3000 µg mL<sup>−1</sup> was effective only on <i>L. multiflorum</i>. In addition, the cytogenotoxic activity evaluation revealed that there was a reduction in the mitotic index and an increase in chromosomal abnormalities. The produced ICs were able to protect the EO and <i>β</i>-CAR from volatility and degradation, with a high thermal stability, and they also enabled the solubilization of the EO and <i>β</i>-CAR in water without the addition of an organic solvent. Therefore, it is possible to indicate the obtained products as potential candidates for commercial exploration since the ICs allow the complexed EO to exhibit a more stable chemical constitution than pure EO under storage conditions.https://www.mdpi.com/1420-3049/28/15/5909natural productaraçáinclusion complexbiological activitybioherbicide |
| spellingShingle | Luiza Alves Mendes Loren Cristina Vasconcelos Milene Miranda Praça Fontes Geisiele Silva Martins Aline dos Santos Bergamin Matheus Alves Silva Rafael Resende Assis Silva Taíla Veloso de Oliveira Victor Gomes Lauriano Souza Marcia Flores da Silva Ferreira Róbson Ricardo Teixeira Renata Pereira Lopes Herbicide and Cytogenotoxic Activity of Inclusion Complexes of <i>Psidium gaudichaudianum</i> Leaf Essential Oil and <i>β</i>-Caryophyllene on 2-Hydroxypropyl-<i>β</i>-cyclodextrin Molecules natural product araçá inclusion complex biological activity bioherbicide |
| title | Herbicide and Cytogenotoxic Activity of Inclusion Complexes of <i>Psidium gaudichaudianum</i> Leaf Essential Oil and <i>β</i>-Caryophyllene on 2-Hydroxypropyl-<i>β</i>-cyclodextrin |
| title_full | Herbicide and Cytogenotoxic Activity of Inclusion Complexes of <i>Psidium gaudichaudianum</i> Leaf Essential Oil and <i>β</i>-Caryophyllene on 2-Hydroxypropyl-<i>β</i>-cyclodextrin |
| title_fullStr | Herbicide and Cytogenotoxic Activity of Inclusion Complexes of <i>Psidium gaudichaudianum</i> Leaf Essential Oil and <i>β</i>-Caryophyllene on 2-Hydroxypropyl-<i>β</i>-cyclodextrin |
| title_full_unstemmed | Herbicide and Cytogenotoxic Activity of Inclusion Complexes of <i>Psidium gaudichaudianum</i> Leaf Essential Oil and <i>β</i>-Caryophyllene on 2-Hydroxypropyl-<i>β</i>-cyclodextrin |
| title_short | Herbicide and Cytogenotoxic Activity of Inclusion Complexes of <i>Psidium gaudichaudianum</i> Leaf Essential Oil and <i>β</i>-Caryophyllene on 2-Hydroxypropyl-<i>β</i>-cyclodextrin |
| title_sort | herbicide and cytogenotoxic activity of inclusion complexes of i psidium gaudichaudianum i leaf essential oil and i β i caryophyllene on 2 hydroxypropyl i β i cyclodextrin |
| topic | natural product araçá inclusion complex biological activity bioherbicide |
| url | https://www.mdpi.com/1420-3049/28/15/5909 |
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