The Effects of Bisphosphonate Therapy on Upper Gastrointestinal Tract in Postmenopausal Women: A Preliminary Report
The aim of this study was to evaluate adverse effects of risedronate, which is effective in the treatment of the osteoporosis, using endoscopic and histopathologic examinations. In all subjects, the endoscopic appearance of the esophageal, gastric and duodenal mucosa was evaluated before the treatme...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2002-09-01
|
| Series: | Türk Osteoporoz Dergisi |
| Subjects: | |
| Online Access: | http://www.turkosteoporozdergisi.org/article_4040/The-Effects-Of-Bisphosphonate-Therapy-On-Upper-Gastrointestinal-Tract-Inpostmenopausal-Women-A-Preliminary-Report |
| _version_ | 1797920711992410112 |
|---|---|
| author | Zeliha Ünlü Murat Saruç Nurten Türkel Küçükmetin Işıl Tuzcuoğlu Mengü Sarıoğlu Semin Ayhan Çiğdem Tüzün Hakan Yüceyar |
| author_facet | Zeliha Ünlü Murat Saruç Nurten Türkel Küçükmetin Işıl Tuzcuoğlu Mengü Sarıoğlu Semin Ayhan Çiğdem Tüzün Hakan Yüceyar |
| author_sort | Zeliha Ünlü |
| collection | DOAJ |
| description | The aim of this study was to evaluate adverse effects of risedronate, which is effective in the treatment of the osteoporosis, using endoscopic and histopathologic examinations. In all subjects, the endoscopic appearance of the esophageal, gastric and duodenal mucosa was evaluated before the treatment. Subjects who had normal endoscopic examination results were given 5 mg/day risedronate, 1000mg/day calcium and 400IU/day vitamin D medication. Endoscopic examinations of eight patients were repeated 1 month later. Control endoscopic and histopathologic examinations revealed gastric damage in 5 of the 8 patients. In conclusion, this preliminary report showed that we should be aware of the gastric damage due to risedronate therapy in the short term period. |
| first_indexed | 2024-04-10T14:05:23Z |
| format | Article |
| id | doaj.art-3e752b6cfaf5420489e6f0057a30f0dc |
| institution | Directory Open Access Journal |
| issn | 2147-2653 |
| language | English |
| last_indexed | 2024-04-10T14:05:23Z |
| publishDate | 2002-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Osteoporoz Dergisi |
| spelling | doaj.art-3e752b6cfaf5420489e6f0057a30f0dc2023-02-15T16:09:59ZengGalenos YayineviTürk Osteoporoz Dergisi2147-26532002-09-0183125127The Effects of Bisphosphonate Therapy on Upper Gastrointestinal Tract in Postmenopausal Women: A Preliminary ReportZeliha Ünlü0Murat Saruç1Nurten Türkel Küçükmetin2Işıl Tuzcuoğlu3Mengü Sarıoğlu4Semin Ayhan5Çiğdem Tüzün6Hakan Yüceyar7Celal Bayar Üniversitesi Tıp Fakültesi Fiziksel Tedavi ve Rehebilitasyon Anabilim DalıCelal Bayar Üniversitesi Tıp Fakültesi Gastroenteroloji Bilim DalıCelal Bayar Üniversitesi Tıp Fakültesi Gastroenteroloji Bilim DalıCelal Bayar Üniversitesi Tıp Fakültesi Gastroenteroloji Bilim DalıCelal Bayar Üniversitesi Tıp Fakültesi Fiziksel Tedavi ve Rehebilitasyon Anabilim DalıCelal Bayar Üniversitesi Tıp Fakültesi Patoloji Anabilim DalıCelal Bayar Üniversitesi Tıp Fakültesi Fiziksel Tedavi ve Rehebilitasyon Anabilim DalıCelal Bayar Üniversitesi Tıp Fakültesi Gastroenteroloji Bilim DalıThe aim of this study was to evaluate adverse effects of risedronate, which is effective in the treatment of the osteoporosis, using endoscopic and histopathologic examinations. In all subjects, the endoscopic appearance of the esophageal, gastric and duodenal mucosa was evaluated before the treatment. Subjects who had normal endoscopic examination results were given 5 mg/day risedronate, 1000mg/day calcium and 400IU/day vitamin D medication. Endoscopic examinations of eight patients were repeated 1 month later. Control endoscopic and histopathologic examinations revealed gastric damage in 5 of the 8 patients. In conclusion, this preliminary report showed that we should be aware of the gastric damage due to risedronate therapy in the short term period.http://www.turkosteoporozdergisi.org/article_4040/The-Effects-Of-Bisphosphonate-Therapy-On-Upper-Gastrointestinal-Tract-Inpostmenopausal-Women-A-Preliminary-ReportOsteoporosisbisphosphonatesgastric damage |
| spellingShingle | Zeliha Ünlü Murat Saruç Nurten Türkel Küçükmetin Işıl Tuzcuoğlu Mengü Sarıoğlu Semin Ayhan Çiğdem Tüzün Hakan Yüceyar The Effects of Bisphosphonate Therapy on Upper Gastrointestinal Tract in Postmenopausal Women: A Preliminary Report Türk Osteoporoz Dergisi Osteoporosis bisphosphonates gastric damage |
| title | The Effects of Bisphosphonate Therapy on Upper Gastrointestinal Tract in Postmenopausal Women: A Preliminary Report |
| title_full | The Effects of Bisphosphonate Therapy on Upper Gastrointestinal Tract in Postmenopausal Women: A Preliminary Report |
| title_fullStr | The Effects of Bisphosphonate Therapy on Upper Gastrointestinal Tract in Postmenopausal Women: A Preliminary Report |
| title_full_unstemmed | The Effects of Bisphosphonate Therapy on Upper Gastrointestinal Tract in Postmenopausal Women: A Preliminary Report |
| title_short | The Effects of Bisphosphonate Therapy on Upper Gastrointestinal Tract in Postmenopausal Women: A Preliminary Report |
| title_sort | effects of bisphosphonate therapy on upper gastrointestinal tract in postmenopausal women a preliminary report |
| topic | Osteoporosis bisphosphonates gastric damage |
| url | http://www.turkosteoporozdergisi.org/article_4040/The-Effects-Of-Bisphosphonate-Therapy-On-Upper-Gastrointestinal-Tract-Inpostmenopausal-Women-A-Preliminary-Report |
| work_keys_str_mv | AT zelihaunlu theeffectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT muratsaruc theeffectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT nurtenturkelkucukmetin theeffectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT isıltuzcuoglu theeffectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT mengusarıoglu theeffectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT seminayhan theeffectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT cigdemtuzun theeffectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT hakanyuceyar theeffectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT zelihaunlu effectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT muratsaruc effectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT nurtenturkelkucukmetin effectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT isıltuzcuoglu effectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT mengusarıoglu effectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT seminayhan effectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT cigdemtuzun effectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport AT hakanyuceyar effectsofbisphosphonatetherapyonuppergastrointestinaltractinpostmenopausalwomenapreliminaryreport |