Paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma: A rare case
Key Clinical Message This case report emphasizes that we should analyze a patient's signs and symptoms as a whole rather than relying exclusively on a common pattern to diagnose the condition and indicates that thorough histological investigation and sample collection are needed to accurately d...
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| Format: | Article |
| Language: | English |
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Wiley
2023-05-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.7348 |
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| author | Elham Paraandavaji Homa Hadidi Mahtab Norouzi Maryam Azaddehghan Mohadeseh Khodaparasti Sasan Shafiei Erfan Ghadirzadeh Seyyed Mojtaba Nekooghadam Hanie Karimi |
| author_facet | Elham Paraandavaji Homa Hadidi Mahtab Norouzi Maryam Azaddehghan Mohadeseh Khodaparasti Sasan Shafiei Erfan Ghadirzadeh Seyyed Mojtaba Nekooghadam Hanie Karimi |
| author_sort | Elham Paraandavaji |
| collection | DOAJ |
| description | Key Clinical Message This case report emphasizes that we should analyze a patient's signs and symptoms as a whole rather than relying exclusively on a common pattern to diagnose the condition and indicates that thorough histological investigation and sample collection are needed to accurately diagnose this malignancy. Abstract Angiosarcoma is a rare, fatal, and poorly understood malignant tumor of vascular endothelial cells which is a challenging disease to diagnose in the clinical settings and requires early diagnosis to achieve a favorable prognosis. Paraneoplastic syndromes associated with angiosarcoma can include hypercoagulability, thrombocytopenia, anemia, fever, weight loss, and night sweats. In some cases, the paraneoplastic syndrome can be the first sign of the underlying malignancy. Here, we present a 47‐year‐old individual with angiosarcoma over the right scapula accompanied by hemoptysis and other pulmonary complaints whom at first was thought to be metastatic polmunary involvement. However, the patient's dramatic response to corticosteroids, in addition to further imaging and paraclinical studies, led us to an acute eosinophilic pneumonia (AEP) diagnosis which is an eosinophilic infiltrations of alveolar spaces. The patient received chemotherapy for angiosarcoma and radiation, since the brachial nerve network was disrupted, leaving the tumor unresectable. After 3 years of continuous follow‐up, the patient is now completely cured. |
| first_indexed | 2024-03-13T09:38:14Z |
| format | Article |
| id | doaj.art-3e75f89659824fbc8f4af1e6d566b407 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-13T09:38:14Z |
| publishDate | 2023-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-3e75f89659824fbc8f4af1e6d566b4072023-05-25T05:58:40ZengWileyClinical Case Reports2050-09042023-05-01115n/an/a10.1002/ccr3.7348Paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma: A rare caseElham Paraandavaji0Homa Hadidi1Mahtab Norouzi2Maryam Azaddehghan3Mohadeseh Khodaparasti4Sasan Shafiei5Erfan Ghadirzadeh6Seyyed Mojtaba Nekooghadam7Hanie Karimi8Skull Base Research Center, Loghman Hakim Hospital Shahid Beheshti University of Medical Sciences Tehran IranKermanshah University of Medical Science Kermanshah IranKermanshah University of Medical Science Kermanshah IranTehran University of Medical Sciences, School of Medicine Tehran IranHormozgan University of Medical Science Bandar Abbas IranSkull Base Research Center, Loghman Hakim Hospital Shahid Beheshti University of Medical Sciences Tehran IranResearch Assistant, Gastroenterology, and Liver Diseases Research Center Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences Tehran IranAssistant Professor of Internal Medicine, Department of Internal Medicine School of Medicine, Shahid Beheshti University of Medical Sciences Tehran IranSchool of Medicine, Tehran University of Medical Sciences Tehran IranKey Clinical Message This case report emphasizes that we should analyze a patient's signs and symptoms as a whole rather than relying exclusively on a common pattern to diagnose the condition and indicates that thorough histological investigation and sample collection are needed to accurately diagnose this malignancy. Abstract Angiosarcoma is a rare, fatal, and poorly understood malignant tumor of vascular endothelial cells which is a challenging disease to diagnose in the clinical settings and requires early diagnosis to achieve a favorable prognosis. Paraneoplastic syndromes associated with angiosarcoma can include hypercoagulability, thrombocytopenia, anemia, fever, weight loss, and night sweats. In some cases, the paraneoplastic syndrome can be the first sign of the underlying malignancy. Here, we present a 47‐year‐old individual with angiosarcoma over the right scapula accompanied by hemoptysis and other pulmonary complaints whom at first was thought to be metastatic polmunary involvement. However, the patient's dramatic response to corticosteroids, in addition to further imaging and paraclinical studies, led us to an acute eosinophilic pneumonia (AEP) diagnosis which is an eosinophilic infiltrations of alveolar spaces. The patient received chemotherapy for angiosarcoma and radiation, since the brachial nerve network was disrupted, leaving the tumor unresectable. After 3 years of continuous follow‐up, the patient is now completely cured.https://doi.org/10.1002/ccr3.7348acute eosinophilic pneumoniaangiosarcomabronchoalveolar lavageeosinophilic lung diseaseeosinophilic pneumoniaparaneoplastic disorder |
| spellingShingle | Elham Paraandavaji Homa Hadidi Mahtab Norouzi Maryam Azaddehghan Mohadeseh Khodaparasti Sasan Shafiei Erfan Ghadirzadeh Seyyed Mojtaba Nekooghadam Hanie Karimi Paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma: A rare case Clinical Case Reports acute eosinophilic pneumonia angiosarcoma bronchoalveolar lavage eosinophilic lung disease eosinophilic pneumonia paraneoplastic disorder |
| title | Paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma: A rare case |
| title_full | Paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma: A rare case |
| title_fullStr | Paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma: A rare case |
| title_full_unstemmed | Paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma: A rare case |
| title_short | Paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma: A rare case |
| title_sort | paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma a rare case |
| topic | acute eosinophilic pneumonia angiosarcoma bronchoalveolar lavage eosinophilic lung disease eosinophilic pneumonia paraneoplastic disorder |
| url | https://doi.org/10.1002/ccr3.7348 |
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