Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
Conventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-14979-6 |
| _version_ | 1818978808170020864 |
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| author | José M. Alvarez Anna-Lena Schinke Matthew D. Brooks Angelo Pasquino Lauriebeth Leonelli Kranthi Varala Alaeddine Safi Gabriel Krouk Anne Krapp Gloria M. Coruzzi |
| author_facet | José M. Alvarez Anna-Lena Schinke Matthew D. Brooks Angelo Pasquino Lauriebeth Leonelli Kranthi Varala Alaeddine Safi Gabriel Krouk Anne Krapp Gloria M. Coruzzi |
| author_sort | José M. Alvarez |
| collection | DOAJ |
| description | Conventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a rapid nitrogen-response cascade. |
| first_indexed | 2024-12-20T16:49:31Z |
| format | Article |
| id | doaj.art-3e7c1767b2d34c089055f0b932128ac5 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T16:49:31Z |
| publishDate | 2020-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-3e7c1767b2d34c089055f0b932128ac52022-12-21T19:32:51ZengNature PortfolioNature Communications2041-17232020-03-0111111310.1038/s41467-020-14979-6Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascadeJosé M. Alvarez0Anna-Lena Schinke1Matthew D. Brooks2Angelo Pasquino3Lauriebeth Leonelli4Kranthi Varala5Alaeddine Safi6Gabriel Krouk7Anne Krapp8Gloria M. Coruzzi9Center for Genomics and Systems Biology, New York UniversityCenter for Genomics and Systems Biology, New York UniversityCenter for Genomics and Systems Biology, New York UniversityCenter for Genomics and Systems Biology, New York UniversityCenter for Genomics and Systems Biology, New York UniversityDepartment of Horticulture and Landscape Architecture, Purdue UniversityBPMP, Université de Montpellier, CNRS, INRA, SupAgroBPMP, Université de Montpellier, CNRS, INRA, SupAgroInstitut Jean-Pierre Bourgin, INRAE, AgroParisTech, Université Paris-SaclayCenter for Genomics and Systems Biology, New York UniversityConventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a rapid nitrogen-response cascade.https://doi.org/10.1038/s41467-020-14979-6 |
| spellingShingle | José M. Alvarez Anna-Lena Schinke Matthew D. Brooks Angelo Pasquino Lauriebeth Leonelli Kranthi Varala Alaeddine Safi Gabriel Krouk Anne Krapp Gloria M. Coruzzi Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade Nature Communications |
| title | Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
| title_full | Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
| title_fullStr | Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
| title_full_unstemmed | Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
| title_short | Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade |
| title_sort | transient genome wide interactions of the master transcription factor nlp7 initiate a rapid nitrogen response cascade |
| url | https://doi.org/10.1038/s41467-020-14979-6 |
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