Influence of 12-bit and 16-bit CT values of metals on dose calculation in radiotherapy using PRIMO, a Monte Carlo code for clinical linear accelerators

In this paper, the effect of computed tomography (CT) values of metals in 12-bit and 16-bit extended Hounsfield Unit (EHU) scale on dose calculations in radiotherapy treatment planning systems (TPS) were quantified. Dose simulations for metals in water environment were performed with the software PR...

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Main Authors: Ese Zehra, Zylka Waldemar
Format: Article
Language:English
Published: De Gruyter 2019-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2019-0150
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author Ese Zehra
Zylka Waldemar
author_facet Ese Zehra
Zylka Waldemar
author_sort Ese Zehra
collection DOAJ
description In this paper, the effect of computed tomography (CT) values of metals in 12-bit and 16-bit extended Hounsfield Unit (EHU) scale on dose calculations in radiotherapy treatment planning systems (TPS) were quantified. Dose simulations for metals in water environment were performed with the software PRIMO in 6MV photon mode. The depth dose profiles were analysed and the relative dose differences between the metals determined with 12-bit and 16-bit CT imaging, respectively, were calculated. Maximum dose differences of ΔAl = 3.0%, ΔTi = 4.5%, ΔCr = 6.2% and ΔCu = 11.6% were measured. In order to increase the accuracy of dose calculation on patients with implants, CT imaging in the EHU scale is recommended.
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spelling doaj.art-3e7e14ed365e451b8a2f9d612e6806a62022-12-22T02:43:48ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042019-09-015159760010.1515/cdbme-2019-0150cdbme-2019-0150Influence of 12-bit and 16-bit CT values of metals on dose calculation in radiotherapy using PRIMO, a Monte Carlo code for clinical linear acceleratorsEse Zehra0Zylka Waldemar1Department of Electrical Engineering and Applied Natural Science, Westphalian University, CampusGelsenkirchen, GermanyDepartment of Electrical Engineering and Applied Natural Science, Westphalian University, CampusGelsenkirchen, GermanyIn this paper, the effect of computed tomography (CT) values of metals in 12-bit and 16-bit extended Hounsfield Unit (EHU) scale on dose calculations in radiotherapy treatment planning systems (TPS) were quantified. Dose simulations for metals in water environment were performed with the software PRIMO in 6MV photon mode. The depth dose profiles were analysed and the relative dose differences between the metals determined with 12-bit and 16-bit CT imaging, respectively, were calculated. Maximum dose differences of ΔAl = 3.0%, ΔTi = 4.5%, ΔCr = 6.2% and ΔCu = 11.6% were measured. In order to increase the accuracy of dose calculation on patients with implants, CT imaging in the EHU scale is recommended.https://doi.org/10.1515/cdbme-2019-0150computed tomographyradiotherapyprimomonte carlo simulation
spellingShingle Ese Zehra
Zylka Waldemar
Influence of 12-bit and 16-bit CT values of metals on dose calculation in radiotherapy using PRIMO, a Monte Carlo code for clinical linear accelerators
Current Directions in Biomedical Engineering
computed tomography
radiotherapy
primo
monte carlo simulation
title Influence of 12-bit and 16-bit CT values of metals on dose calculation in radiotherapy using PRIMO, a Monte Carlo code for clinical linear accelerators
title_full Influence of 12-bit and 16-bit CT values of metals on dose calculation in radiotherapy using PRIMO, a Monte Carlo code for clinical linear accelerators
title_fullStr Influence of 12-bit and 16-bit CT values of metals on dose calculation in radiotherapy using PRIMO, a Monte Carlo code for clinical linear accelerators
title_full_unstemmed Influence of 12-bit and 16-bit CT values of metals on dose calculation in radiotherapy using PRIMO, a Monte Carlo code for clinical linear accelerators
title_short Influence of 12-bit and 16-bit CT values of metals on dose calculation in radiotherapy using PRIMO, a Monte Carlo code for clinical linear accelerators
title_sort influence of 12 bit and 16 bit ct values of metals on dose calculation in radiotherapy using primo a monte carlo code for clinical linear accelerators
topic computed tomography
radiotherapy
primo
monte carlo simulation
url https://doi.org/10.1515/cdbme-2019-0150
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AT zylkawaldemar influenceof12bitand16bitctvaluesofmetalsondosecalculationinradiotherapyusingprimoamontecarlocodeforclinicallinearaccelerators