Phosphate Starvation by Energy Metabolism Disturbance in <i>Candida albicans</i><i>vip1</i>Δ/Δ Induces Lipid Droplet Accumulation and Cell Membrane Damage

Phosphate Starvation by Energy Metabolism Disturbance in <i>Candida albicans</i><i>vip1</i>Δ/Δ Induces Lipid Droplet Accumulation and Cell Membrane Damage

Phosphorus in the form of phosphate (Pi) is an essential element for metabolic processes, including lipid metabolism. In yeast, the inositol polyphosphate kinase <i>vip1</i> mediated synthesis of inositol heptakisphosphate (IP<sub>7</sub>) regulates the phosphate-responsive (...

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Bibliographic Details
Main Authors: Xueling Peng, Congcong Ma, Yuxin Feng, Biao Zhang, Mengsen Zhu, Tianyu Ma, Qilin Yu, Mingchun Li
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
PHO pathway
phosphate stress
lipid droplet
Online Access:https://www.mdpi.com/1420-3049/27/3/686

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