Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses
Alave-Furrer et al adapted their recently-developed 3D bioprinting platform to allow microvalve-based drop-on-demand printing of cell-laden Matrigel containing primary human muscle precursor cells. Their bioprinting platform recapitulated aspects of exercise and pharmacological responses and thus co...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-10-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02691-0 |
| _version_ | 1819148599240425472 |
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| author | Angela Alave Reyes-Furrer Sonia De Andrade Dominic Bachmann Heidi Jeker Martin Steinmann Nathalie Accart Andrew Dunbar Martin Rausch Epifania Bono Markus Rimann Hansjoerg Keller |
| author_facet | Angela Alave Reyes-Furrer Sonia De Andrade Dominic Bachmann Heidi Jeker Martin Steinmann Nathalie Accart Andrew Dunbar Martin Rausch Epifania Bono Markus Rimann Hansjoerg Keller |
| author_sort | Angela Alave Reyes-Furrer |
| collection | DOAJ |
| description | Alave-Furrer et al adapted their recently-developed 3D bioprinting platform to allow microvalve-based drop-on-demand printing of cell-laden Matrigel containing primary human muscle precursor cells. Their bioprinting platform recapitulated aspects of exercise and pharmacological responses and thus could aid the engineering of more complex 3D microphysiological systems. |
| first_indexed | 2024-12-22T13:48:16Z |
| format | Article |
| id | doaj.art-3e8c0388474b4dcdac2c6f21af3426d5 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-12-22T13:48:16Z |
| publishDate | 2021-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-3e8c0388474b4dcdac2c6f21af3426d52022-12-21T18:23:44ZengNature PortfolioCommunications Biology2399-36422021-10-014111210.1038/s42003-021-02691-0Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responsesAngela Alave Reyes-Furrer0Sonia De Andrade1Dominic Bachmann2Heidi Jeker3Martin Steinmann4Nathalie Accart5Andrew Dunbar6Martin Rausch7Epifania Bono8Markus Rimann9Hansjoerg Keller10Musculoskeletal Disease Area, Novartis Institutes for BioMedical ResearchMusculoskeletal Disease Area, Novartis Institutes for BioMedical ResearchMusculoskeletal Disease Area, Novartis Institutes for BioMedical ResearchMusculoskeletal Disease Area, Novartis Institutes for BioMedical ResearchAnalytical Sciences & Imaging, Novartis Institutes for BioMedical ResearchMusculoskeletal Disease Area, Novartis Institutes for BioMedical ResearchAnalytical Sciences & Imaging, Novartis Institutes for BioMedical ResearchAnalytical Sciences & Imaging, Novartis Institutes for BioMedical Research3D Tissues and Biofabrication, Institute of Chemistry and Biotechnology (ICBT), Zurich University of Applied Sciences3D Tissues and Biofabrication, Institute of Chemistry and Biotechnology (ICBT), Zurich University of Applied SciencesMusculoskeletal Disease Area, Novartis Institutes for BioMedical ResearchAlave-Furrer et al adapted their recently-developed 3D bioprinting platform to allow microvalve-based drop-on-demand printing of cell-laden Matrigel containing primary human muscle precursor cells. Their bioprinting platform recapitulated aspects of exercise and pharmacological responses and thus could aid the engineering of more complex 3D microphysiological systems.https://doi.org/10.1038/s42003-021-02691-0 |
| spellingShingle | Angela Alave Reyes-Furrer Sonia De Andrade Dominic Bachmann Heidi Jeker Martin Steinmann Nathalie Accart Andrew Dunbar Martin Rausch Epifania Bono Markus Rimann Hansjoerg Keller Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses Communications Biology |
| title | Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses |
| title_full | Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses |
| title_fullStr | Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses |
| title_full_unstemmed | Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses |
| title_short | Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses |
| title_sort | matrigel 3d bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses |
| url | https://doi.org/10.1038/s42003-021-02691-0 |
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