CRISPR-Cas12a-Empowered Electrochemical Biosensor for Rapid and Ultrasensitive Detection of SARS-CoV-2 Delta Variant

CRISPR-Cas12a-Empowered Electrochemical Biosensor for Rapid and Ultrasensitive Detection of SARS-CoV-2 Delta Variant

Abstract Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gold standard method for the diagnosis of SARS-CoV-2 depends on quantitative reverse transcription-polymerase chain reaction till now, which is time...

Full description

Bibliographic Details
Main Authors:	Chenshuo Wu, Zhi Chen, Chaozhou Li, Yabin Hao, Yuxuan Tang, Yuxuan Yuan, Luxiao Chai, Taojian Fan, Jiangtian Yu, Xiaopeng Ma, Omar A. Al-Hartomy, S. Wageh, Abdullah G. Al-Sehemi, Zhiguang Luo, Yaqing He, Jingfeng Li, Zhongjian Xie, Han Zhang
Format:	Article
Language:	English
Published:	SpringerOpen 2022-08-01
Series:	Nano-Micro Letters
Subjects:	SARS-COV-2 variant Methodology of electrochemical CRISPR sensing (MOECS) Gold nanoparticles (AuNPs) Point-of-care testing (POCT)
Online Access:	https://doi.org/10.1007/s40820-022-00888-4

Similar Items

Gold Nanoparticle-Based Colorimetric Strategies for Chemical and Biological Sensing Applications
by: Chia-Chen Chang, et al.
Published: (2019-06-01)

Electrochemical Aptasensor for Myoglobin-Specific Recognition Based on Porphyrin Functionalized Graphene-Conjugated Gold Nanocomposites
by: Guojuan Zhang, et al.
Published: (2016-10-01)

Development of a Smartphone-Based Nanozyme-Linked Immunosorbent Assay for Quantitative Detection of SARS-CoV-2 Nucleocapsid Phosphoprotein in Blood
by: Bochao Liu, et al.
Published: (2021-08-01)

Development of gold nanoparticles biosensor for ultrasensitive diagnosis of foot and mouth disease virus
by: Mervat E. Hamdy, et al.
Published: (2018-05-01)

Based on Unmodified Aptamer-Gold Nanoparticles Colorimetric Detection of Dexamethasone in Food
by: Yadi Qin, et al.
Published: (2022-04-01)

Fast and Low-Cost Surface-Enhanced Raman Scattering (SERS) Method for On-Site Detection of Flumetsulam in Wheat
by: Mingming Han, et al.
Published: (2020-10-01)

Plasma-Assisted Synthesis of Surfactant-Free and D-Fructose-Coated Gold Nanoparticles for Multiple Applications
by: Hafiz M. Yasin, et al.
Published: (2022-10-01)

Development of bio fabricated gold nanoparticles for disinfectant applications in impregnated medical gloves to improve the personal protection during the nursing care
by: Yuanyuan Yan, et al.
Published: (2022-01-01)

Enhancement of Antibacterial Activity of Face Mask with Gold Nanoparticles
by: Farah sadiq Khasro, et al.
Published: (2022-07-01)

Microarray analysis of Arabidopsis under gold exposure to identify putative genes involved in the synthesis of gold nanoparticles (AuNPs)
by: Devesh Shukla, et al.
Published: (2015-03-01)

Highly Sensitive Love Mode Acoustic Wave Platform with SiO<sub>2</sub> Wave-Guiding Layer and Gold Nanoparticles for Detection of Carcinoembryonic Antigens
by: Chong Li, et al.
Published: (2022-07-01)

Green synthesis of gold nanoparticles as an effective opportunity for cancer treatment
by: Ali S. Abed, et al.
Published: (2023-01-01)

The Enhanced Photo-Electrochemical Detection of Uric Acid on Au Nanoparticles Modified Glassy Carbon Electrode
by: Yuting Shi, et al.
Published: (2017-07-01)

Gold nanoparticle should understand protein corona for being a clinical nanomaterial
by: Charbgoo, Fahimeh, et al.
Published: (2020)

A Comparison Study of Functional Groups (Amine vs. Thiol) for Immobilizing AuNPs on Zeolite Surface
by: Xi Rao, et al.
Published: (2019-07-01)

Porphyrins in Competition with their Nanomaterials Containing PtNPs and AuNPs. Synergism for the Benefit of Sensing Applications
by: Eugenia Fagadar-Cosma
Published: (2020-11-01)

Gold nanoparticles: Synthesis properties and applications
by: Inès Hammami, et al.
Published: (2021-10-01)

Biological Performance of Primary Dental Pulp Stem Cells Treated with Gold Nanoparticles
by: Duaa Abuarqoub, et al.
Published: (2023-09-01)

Microalgae Peptide-Stabilized Gold Nanoparticles as a Versatile Material for Biomedical Applications
by: Marielys Torres-Díaz, et al.
Published: (2022-06-01)

Green Synthesis of Gold and Silver Nanoparticles by Using <i>Amorphophallus paeoniifolius</i> Tuber Extract and Evaluation of Their Antibacterial Activity
by: S. M. Abu Nayem, et al.
Published: (2020-10-01)

Synthesis of Xylan-Click-Quaternized Chitosan via Click Chemistry and Its Application in the Preparation of Nanometal Materials
by: Yuqiong Luo, et al.
Published: (2022-05-01)

Self-Assembled Monolayers for Uricase Enzyme Absorption Immobilization on Screen-Printed Gold Electrodes Modified
by: Héctor David Hernández, et al.
Published: (2023-05-01)

Design and Characterization of pMyc/pMax Peptide-Coupled Gold Nanosystems for Targeting Myc in Prostate Cancer Cell Lines
by: Samuel Longoria-García, et al.
Published: (2023-10-01)

pMyc and pMax Peptides Nanosystems and the Potential Treatment of Prostate Cancer, In Vitro Assays
by: Samuel Longoria-García, et al.
Published: (2023-05-01)

ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine
by: Jiaying Cao, et al.
Published: (2021-11-01)

The Integration of Gold Nanoparticles with Polymerase Chain Reaction for Constructing Colorimetric Sensing Platforms for Detection of Health-Related DNA and Proteins
by: Wanhe Wang, et al.
Published: (2022-06-01)

Screening of Single-Stranded DNA Aptamer Specific for Florfenicol and Application in Detection of Food Safety
by: Minghui Shi, et al.
Published: (2022-09-01)

The anti-angiogenesis and antioxidant activity of chitosan-mediated synthesized selenium-gold nanostructure
by: Hoda Zarharan, et al.
Published: (2023-07-01)

Highly sensitive and selective amperometric hydrazine sensor based on Au nanoparticle-decorated conducting polythiophene prepared via oxidative polymerization and photo-reduction techniques
by: Md.A. Rashed, et al.
Published: (2022-05-01)

Suppression of adipogenesis by Au nanostructures-conjugated Sargassum seaweed extracts in 3 T3-L1 adipocytes
by: Sun Young Park, et al.
Published: (2022-09-01)

Effect of gold nanoparticles (AuNPs) on isolated rat tracheal segments
by: Daniel Alberto Maldonado-Ortega, et al.
Published: (2021-01-01)

Effect of taurine associated gold nanoparticles on oxidative stress in muscle of mice exposed to overuse model
by: ANAND THIRUPATHI, et al.
Published: (2021-05-01)

Non-Covalent Associates of siRNAs and AuNPs Enveloped with Lipid Layer and Doped with Amphiphilic Peptide for Efficient siRNA Delivery
by: Julia Poletaeva, et al.
Published: (2018-07-01)

Disposable Electrochemical Aptasensor Based on Graphene Oxide-DNA Complex as Signal Amplifier towards Ultrasensitive Detection of Ochratoxin A
by: Yang Hu, et al.
Published: (2022-05-01)

An Enhanced Lateral Flow Assay Based on Aptamer–Magnetic Separation and Multifold AuNPs for Ultrasensitive Detection of <i>Salmonella</i> Typhimurium in Milk
by: Pingping Gao, et al.
Published: (2021-07-01)

Novel Microsynthesis of High-Yield Gold Nanoparticles to Accelerate Research in Biosensing and Other Bioapplications
by: Víctor Díaz-García, et al.
Published: (2023-11-01)

Unraveling the Antibiofilm Activity of a New Nanogold Resin for Dentures and Epithesis
by: Vera Ivanovic, et al.
Published: (2022-07-01)

Hemostasis and Anti-Inflammatory Abilities of AuNPs-Coated Chitosan Dressing for Burn Wounds
by: Juin-Hong Cherng, et al.
Published: (2022-06-01)

Three Generations of Surface Nanocomposites Based on Hexagonally Ordered Gold Nanoparticle Layers and Their Application for Surface-Enhanced Raman Spectroscopy
by: Shireen Zangana, et al.
Published: (2023-04-01)

Rapid Sonochemically-Assisted Synthesis of Highly Stable Gold Nanoparticles as Computed Tomography Contrast Agents
by: Mohammed Ali Dheyab, et al.
Published: (2020-10-01)