Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD).

Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD).

Smoke exposure is known to decrease total pulmonary surfactant and alter its composition, but the role of surfactant in chronic obstructive pulmonary disease (COPD) remains unknown. We aimed to analyze the compositional changes in the surfactant lipidome in COPD and identify specific lipids associat...

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Bibliographic Details
Main Authors: Christina W Agudelo, Britta K Kumley, Estela Area-Gomez, Yimeng Xu, Abdoulaye J Dabo, Patrick Geraghty, Michael Campos, Robert Foronjy, Itsaso Garcia-Arcos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0228279

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