The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study
Abstract Few studies have investigated the relationship between blood type and trauma outcomes according to the type of injury. We conducted a retrospective multicenter observational study in twelve emergency hospitals in Japan. Patients with isolated severe abdominal injury (abbreviated injury scal...
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| Format: | Article |
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Nature Portfolio
2021-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-95443-3 |
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| author | Wataru Takayama Akira Endo Kiyoshi Murata Kota Hoshino Shiei Kim Hiroharu Shinozaki Keisuke Harada Hiroaki Nagano Masahiro Hagiwara Atsuhito Tsuchihashi Nagato Shimada Naomi Kitamura Shunsuke Kuramoto Yasuhiro Otomo |
| author_facet | Wataru Takayama Akira Endo Kiyoshi Murata Kota Hoshino Shiei Kim Hiroharu Shinozaki Keisuke Harada Hiroaki Nagano Masahiro Hagiwara Atsuhito Tsuchihashi Nagato Shimada Naomi Kitamura Shunsuke Kuramoto Yasuhiro Otomo |
| author_sort | Wataru Takayama |
| collection | DOAJ |
| description | Abstract Few studies have investigated the relationship between blood type and trauma outcomes according to the type of injury. We conducted a retrospective multicenter observational study in twelve emergency hospitals in Japan. Patients with isolated severe abdominal injury (abbreviated injury scale for the abdomen ≥ 3 and that for other organs < 3) that occurred between 2008 and 2018 were divided into four groups according to blood type. The association between blood type and mortality, ventilator-free days (VFD), and total transfusion volume were evaluated using univariate and multivariate regression models. A total of 920 patients were included, and were divided based on their blood type: O, 288 (31%); A, 345 (38%); B, 186 (20%); and AB, 101 (11%). Patients with type O had a higher in-hospital mortality rate than those of other blood types (22% vs. 13%, p < 0.001). This association was observed in multivariate analysis (adjusted odds ratio [95% confidence interval] = 1.48 [1.25–2.26], p = 0.012). Furthermore, type O was associated with significantly higher cause-specific mortalities, fewer VFD, and larger transfusion volumes. Blood type O was associated with significantly higher mortality and larger transfusion volumes in patients with isolated severe abdominal trauma. |
| first_indexed | 2024-12-23T03:30:37Z |
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| id | doaj.art-3e8f59029029467aab0c5391b715917b |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-23T03:30:37Z |
| publishDate | 2021-08-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj.art-3e8f59029029467aab0c5391b715917b2022-12-21T18:01:41ZengNature PortfolioScientific Reports2045-23222021-08-011111810.1038/s41598-021-95443-3The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational studyWataru Takayama0Akira Endo1Kiyoshi Murata2Kota Hoshino3Shiei Kim4Hiroharu Shinozaki5Keisuke Harada6Hiroaki Nagano7Masahiro Hagiwara8Atsuhito Tsuchihashi9Nagato Shimada10Naomi Kitamura11Shunsuke Kuramoto12Yasuhiro Otomo13Trauma and Acute Critical Care Center, Tokyo Medical and Dental University Hospital of MedicineTrauma and Acute Critical Care Center, Tokyo Medical and Dental University Hospital of MedicineThe Shock Trauma and Emergency Medical Center, Matsudo City General HospitalDepartment of Emergency and Critical Care Medicine, Fukuoka University HospitalDepartment of Emergency and Critical Care Medicine, Nippon Medical School HospitalDepartment of Surgery, Saiseikai Utsunomiya HospitalDepartment of Emergency Medicine, Sapporo Medical UniversityDepartment of Gastroenterological Breast and Endocrine Surgery, Yamaguchi University Graduate School of MedicineDepartment of Surgery, Asahikawa Medical UniversityDepartment Surgery, St. Marianna University School of MedicineDepartment of General Medicine and Emergency Center (Surgery), Toho University Omori Medical CenterDepartment of Surgery, Shiga University of Medical Science HospitalDepartment of Acute Care Surgery, Faculty of Medicine, Shimane UniversityTrauma and Acute Critical Care Center, Tokyo Medical and Dental University Hospital of MedicineAbstract Few studies have investigated the relationship between blood type and trauma outcomes according to the type of injury. We conducted a retrospective multicenter observational study in twelve emergency hospitals in Japan. Patients with isolated severe abdominal injury (abbreviated injury scale for the abdomen ≥ 3 and that for other organs < 3) that occurred between 2008 and 2018 were divided into four groups according to blood type. The association between blood type and mortality, ventilator-free days (VFD), and total transfusion volume were evaluated using univariate and multivariate regression models. A total of 920 patients were included, and were divided based on their blood type: O, 288 (31%); A, 345 (38%); B, 186 (20%); and AB, 101 (11%). Patients with type O had a higher in-hospital mortality rate than those of other blood types (22% vs. 13%, p < 0.001). This association was observed in multivariate analysis (adjusted odds ratio [95% confidence interval] = 1.48 [1.25–2.26], p = 0.012). Furthermore, type O was associated with significantly higher cause-specific mortalities, fewer VFD, and larger transfusion volumes. Blood type O was associated with significantly higher mortality and larger transfusion volumes in patients with isolated severe abdominal trauma.https://doi.org/10.1038/s41598-021-95443-3 |
| spellingShingle | Wataru Takayama Akira Endo Kiyoshi Murata Kota Hoshino Shiei Kim Hiroharu Shinozaki Keisuke Harada Hiroaki Nagano Masahiro Hagiwara Atsuhito Tsuchihashi Nagato Shimada Naomi Kitamura Shunsuke Kuramoto Yasuhiro Otomo The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study Scientific Reports |
| title | The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study |
| title_full | The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study |
| title_fullStr | The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study |
| title_full_unstemmed | The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study |
| title_short | The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study |
| title_sort | impact of blood type on the mortality of patients with severe abdominal trauma a multicenter observational study |
| url | https://doi.org/10.1038/s41598-021-95443-3 |
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