Control of snakebite envenoming: A mathematical modeling study.
A mathematical model is designed to assess the impact of some interventional strategies for curtailing the burden of snakebite envenoming in a community. The model is fitted with real data set. Numerical simulations have shown that public health awareness of the susceptible individuals on snakebite...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-08-01
|
| Series: | PLoS Neglected Tropical Diseases |
| Online Access: | https://doi.org/10.1371/journal.pntd.0009711 |
| _version_ | 1818682180741627904 |
|---|---|
| author | Shuaibu Ahijo Abdullahi Abdulrazaq Garba Habib Nafiu Hussaini |
| author_facet | Shuaibu Ahijo Abdullahi Abdulrazaq Garba Habib Nafiu Hussaini |
| author_sort | Shuaibu Ahijo Abdullahi |
| collection | DOAJ |
| description | A mathematical model is designed to assess the impact of some interventional strategies for curtailing the burden of snakebite envenoming in a community. The model is fitted with real data set. Numerical simulations have shown that public health awareness of the susceptible individuals on snakebite preventive measures could reduce the number of envenoming and prevent deaths and disabilities in the population. The simulations further revealed that if at least fifty percent of snakebite envenoming patients receive early treatment with antivenom a substantial number of deaths will be averted. Furthermore, it is shown using optimal control that combining public health awareness and antivenom treatment averts the highest number of snakebite induced deaths and disability adjusted life years in the study area. To choose the best strategy amidst limited resources in the study area, cost effectiveness analysis in terms of incremental cost effectiveness ratio is performed. It has been established that the control efforts of combining public health awareness of the susceptible individuals and antivenom treatment for victims of snakebite envenoming is the most cost effective strategy. Approximately the sum of US$72,548 is needed to avert 117 deaths or 2,739 disability adjusted life years that are recorded within 21 months in the study area. Thus, the combination of these two control strategies is recommended. |
| first_indexed | 2024-12-17T10:14:45Z |
| format | Article |
| id | doaj.art-3e8fc3cb065f4267a0e1f7a6fb999889 |
| institution | Directory Open Access Journal |
| issn | 1935-2727 1935-2735 |
| language | English |
| last_indexed | 2024-12-17T10:14:45Z |
| publishDate | 2021-08-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Neglected Tropical Diseases |
| spelling | doaj.art-3e8fc3cb065f4267a0e1f7a6fb9998892022-12-21T21:52:56ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352021-08-01158e000971110.1371/journal.pntd.0009711Control of snakebite envenoming: A mathematical modeling study.Shuaibu Ahijo AbdullahiAbdulrazaq Garba HabibNafiu HussainiA mathematical model is designed to assess the impact of some interventional strategies for curtailing the burden of snakebite envenoming in a community. The model is fitted with real data set. Numerical simulations have shown that public health awareness of the susceptible individuals on snakebite preventive measures could reduce the number of envenoming and prevent deaths and disabilities in the population. The simulations further revealed that if at least fifty percent of snakebite envenoming patients receive early treatment with antivenom a substantial number of deaths will be averted. Furthermore, it is shown using optimal control that combining public health awareness and antivenom treatment averts the highest number of snakebite induced deaths and disability adjusted life years in the study area. To choose the best strategy amidst limited resources in the study area, cost effectiveness analysis in terms of incremental cost effectiveness ratio is performed. It has been established that the control efforts of combining public health awareness of the susceptible individuals and antivenom treatment for victims of snakebite envenoming is the most cost effective strategy. Approximately the sum of US$72,548 is needed to avert 117 deaths or 2,739 disability adjusted life years that are recorded within 21 months in the study area. Thus, the combination of these two control strategies is recommended.https://doi.org/10.1371/journal.pntd.0009711 |
| spellingShingle | Shuaibu Ahijo Abdullahi Abdulrazaq Garba Habib Nafiu Hussaini Control of snakebite envenoming: A mathematical modeling study. PLoS Neglected Tropical Diseases |
| title | Control of snakebite envenoming: A mathematical modeling study. |
| title_full | Control of snakebite envenoming: A mathematical modeling study. |
| title_fullStr | Control of snakebite envenoming: A mathematical modeling study. |
| title_full_unstemmed | Control of snakebite envenoming: A mathematical modeling study. |
| title_short | Control of snakebite envenoming: A mathematical modeling study. |
| title_sort | control of snakebite envenoming a mathematical modeling study |
| url | https://doi.org/10.1371/journal.pntd.0009711 |
| work_keys_str_mv | AT shuaibuahijoabdullahi controlofsnakebiteenvenomingamathematicalmodelingstudy AT abdulrazaqgarbahabib controlofsnakebiteenvenomingamathematicalmodelingstudy AT nafiuhussaini controlofsnakebiteenvenomingamathematicalmodelingstudy |