Toolbox for non-intrusive structural and functional analysis of recombinant VLP based vaccines: a case study with hepatitis B vaccine.

Toolbox for non-intrusive structural and functional analysis of recombinant VLP based vaccines: a case study with hepatitis B vaccine.

BACKGROUND: Fundamental to vaccine development, manufacturing consistency, and product stability is an understanding of the vaccine structure-activity relationship. With the virus-like particle (VLP) approach for recombinant vaccines gaining popularity, there is growing demand for tools that define...

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Bibliographic Details
Main Authors: Anke M Mulder, Bridget Carragher, Victoria Towne, Yuan Meng, Yang Wang, Lance Dieter, Clinton S Potter, Michael W Washabaugh, Robert D Sitrin, Qinjian Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3320896?pdf=render

Internet

http://europepmc.org/articles/PMC3320896?pdf=render

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