Flumazenil Pretreatment Reduces Mefenamic Acid-Induced Central Nervous System Toxicity in Mice
Background: Mefenamic acid (MFA), a common analgesic, causes central nervous system (CNS) toxicity at high doses with a proposed activity on the Gamma-aminobutyric acid (GABA) system. However, it remains unknown whether flumazenil (FMZ), a GABA type A receptor (GABAAR) antagonist, can reverse MFA to...
Main Authors: | Qais Jarrar, Rami Ayoub, Yazun Jarrar, Hadeel Aburass, Khang Wen Goh, Chrismawan Ardianto, Long Chiau Ming, Said Moshawih, Hussain Alfaqih |
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Format: | Article |
Language: | English |
Published: |
IMR Press
2023-07-01
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Series: | Journal of Integrative Neuroscience |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/JIN/22/4/10.31083/j.jin2204104 |
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