Combination of Oncolytic Measles Virus Armed With BNiP3, a Pro-apoptotic Gene and Paclitaxel Induces Breast Cancer Cell Death

Combination of Oncolytic Measles Virus Armed With BNiP3, a Pro-apoptotic Gene and Paclitaxel Induces Breast Cancer Cell Death

Breast cancer is one of the major causes of cancer related mortality in women worldwide. Limitations of conventional anti-cancer therapies such as severe systemic side effects, narrow therapeutic index, non-specificity, and non-availability of drugs for all types of cancers has resulted in the devel...

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Bibliographic Details
Main Authors: Geetanjali Lal, Maitreyi S. Rajala
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Oncology
Subjects:
triple negative breast cancer/TNBC
oncolytic virus
measles virus
BNiP3
paclitaxel
combination therapy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00676/full

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