MMP24 as a Target of YAP is a Potential Prognostic Factor in Cancer Patients

MMP24 as a Target of YAP is a Potential Prognostic Factor in Cancer Patients

The extracellular matrix (ECM) surrounding cancer cells becomes stiffer during tumor progression, which influences cancer cell behaviors such as invasion and proliferation through modulation of gene expression as well as remodeling of the actin cytoskeleton. In this study, we show that <i>MMP2...

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Bibliographic Details
Main Authors: Wataru Sugimoto, Katsuhiko Itoh, Hiroaki Hirata, Yoshinori Abe, Takeru Torii, Yasumasa Mitsui, Yemima Budirahardja, Nobuyuki Tanaka, Keiko Kawauchi
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Bioengineering
Subjects:
mmp
yap
ecm
mechanical signal transduction
cancer progression
prognosis
Online Access:https://www.mdpi.com/2306-5354/7/1/18

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