Myocardial protection by ischemic remote conditioning in coronary revascularization

<span style="font-family: Verdana,Arial,Helvetica,sans-serif; font-size: small;"><strong>Introduction:</strong> A series of short periods of distant ischemia, prior to the major ischemic event, can limit the myocardial damage produced by ischemia or reperfusion.<br /&g...

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Bibliographic Details
Main Authors: Rudy Hernández Ortega, Maria Oslaida Agüero Martínez, Osvaldo González Alfonso, María Idoris Cordero Escobar, Teddy Osmín Tamargo Barbeito
Format: Article
Language:Spanish
Published: Centro Nacional de Información de Ciencias Médicas. Editorial de Ciencias Médicas (ECIMED) 2019-01-01
Series:Revista Cubana de Anestesiología y Reanimación
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Online Access:http://revanestesia.sld.cu/index.php/anestRean/article/view/489
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Summary:<span style="font-family: Verdana,Arial,Helvetica,sans-serif; font-size: small;"><strong>Introduction:</strong> A series of short periods of distant ischemia, prior to the major ischemic event, can limit the myocardial damage produced by ischemia or reperfusion.<br /> <strong>Objective:</strong> To evaluate the usefulness of remote ischemic conditioning in patients scheduled for surgical procedures of coronary revascularization.<br /> <strong>Methods:</strong> A quasi-experimental, explanatory, comparative study with historical control was conducted in two groups of 247 patients proposed for coronary revascularization. A tourniquet was placed in the right arm in the study group, alternating 3 insufflations with 3 dessufflations with a pressure of 200 mmHg, keeping each for 5 minutes. This procedure was performed before, during and after the major ischemic event, caused by the impingement of the coronary artery.<br /> <strong>Results:</strong> A significant decrease in enzymatic parameters was achieved. No significant differences were found (p&gt; 0.05) according to a set of variables that represent the initial state of the patients.</span>
ISSN:1726-6718