Similarities and differences of clinical characteristics between Brugada syndrome and early repolarization syndrome
Early repolarization (or J wave) is a common electrocardiographic finding that occurs in 1% to 10% of healthy persons. It has been generally considered benign for decades. However, there is increasing evidence showing that early repolarization is associated with the susceptibility to ventricular fib...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-04-01
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| Series: | Journal of Arrhythmia |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1880427613000148 |
| _version_ | 1818559058169298944 |
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| author | Hiroshi Watanabe Tohru Minamino |
| author_facet | Hiroshi Watanabe Tohru Minamino |
| author_sort | Hiroshi Watanabe |
| collection | DOAJ |
| description | Early repolarization (or J wave) is a common electrocardiographic finding that occurs in 1% to 10% of healthy persons. It has been generally considered benign for decades. However, there is increasing evidence showing that early repolarization is associated with the susceptibility to ventricular fibrillation and sudden cardiac death. Therefore, early repolarization syndrome, or J-wave syndrome, has recently been proposed as a new disease entity. Brugada syndrome is characterized by ST-segment elevation in the right precordial leads (V1 to V3) of a 12-lead electrocardiogram, and is another form of idiopathic ventricular fibrillation associated with J-point elevation. Brugada syndrome and early repolarization syndrome share genetic, clinical, and electrophysiological characteristics, such as causative genes, male dominance, pause-dependent augmentation of J-point elevation, and response to drugs. However, these two diseases also have certain differences. This review focuses on the similarities and differences between Brugada syndrome and early repolarization syndrome, both of which are associated with J-point elevation and sudden cardiac death. |
| first_indexed | 2024-12-14T00:20:24Z |
| format | Article |
| id | doaj.art-3e98223d41ad433ca8f78e22b67a6af4 |
| institution | Directory Open Access Journal |
| issn | 1880-4276 |
| language | English |
| last_indexed | 2024-12-14T00:20:24Z |
| publishDate | 2013-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Arrhythmia |
| spelling | doaj.art-3e98223d41ad433ca8f78e22b67a6af42022-12-21T23:25:14ZengWileyJournal of Arrhythmia1880-42762013-04-0129213413710.1016/j.joa.2013.01.007Similarities and differences of clinical characteristics between Brugada syndrome and early repolarization syndromeHiroshi WatanabeTohru MinaminoEarly repolarization (or J wave) is a common electrocardiographic finding that occurs in 1% to 10% of healthy persons. It has been generally considered benign for decades. However, there is increasing evidence showing that early repolarization is associated with the susceptibility to ventricular fibrillation and sudden cardiac death. Therefore, early repolarization syndrome, or J-wave syndrome, has recently been proposed as a new disease entity. Brugada syndrome is characterized by ST-segment elevation in the right precordial leads (V1 to V3) of a 12-lead electrocardiogram, and is another form of idiopathic ventricular fibrillation associated with J-point elevation. Brugada syndrome and early repolarization syndrome share genetic, clinical, and electrophysiological characteristics, such as causative genes, male dominance, pause-dependent augmentation of J-point elevation, and response to drugs. However, these two diseases also have certain differences. This review focuses on the similarities and differences between Brugada syndrome and early repolarization syndrome, both of which are associated with J-point elevation and sudden cardiac death.http://www.sciencedirect.com/science/article/pii/S1880427613000148ArrhythmiaVentricular fibrillationElectrocardiogramGeneticsTreatment |
| spellingShingle | Hiroshi Watanabe Tohru Minamino Similarities and differences of clinical characteristics between Brugada syndrome and early repolarization syndrome Journal of Arrhythmia Arrhythmia Ventricular fibrillation Electrocardiogram Genetics Treatment |
| title | Similarities and differences of clinical characteristics between Brugada syndrome and early repolarization syndrome |
| title_full | Similarities and differences of clinical characteristics between Brugada syndrome and early repolarization syndrome |
| title_fullStr | Similarities and differences of clinical characteristics between Brugada syndrome and early repolarization syndrome |
| title_full_unstemmed | Similarities and differences of clinical characteristics between Brugada syndrome and early repolarization syndrome |
| title_short | Similarities and differences of clinical characteristics between Brugada syndrome and early repolarization syndrome |
| title_sort | similarities and differences of clinical characteristics between brugada syndrome and early repolarization syndrome |
| topic | Arrhythmia Ventricular fibrillation Electrocardiogram Genetics Treatment |
| url | http://www.sciencedirect.com/science/article/pii/S1880427613000148 |
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