Assessment of endothelial function by flow-mediated dilation of the brachial artery in adolescents with a history of preeclampsia or a normotensive pregnancy

Objectives: to determine the prevalence of endothelial dysfunction and its association with a history of mild and severe preeclampsia in adolescents. Methods: a cross-sectional study was carried out at the MEAC-UFC with 103 primiparous adolescents postpartum. The assessment of endothelial function...

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Bibliographic Details
Main Authors: Joana Adalgisa Furtado Magalhães Andrade, Francisco Herlânio Costa Carvalho, Rosa Maria Salani Mota, Guilherme Augusto Magalhães Andrade, Helvécio Neves Feitosa, Flávio Lúcio Pontes Ibiapina, Francisco das Chagas Medeiros
Format: Article
Language:English
Published: Instituto Materno Infantil de Pernambuco 2014-03-01
Series:Revista Brasileira de Saúde Materno Infantil
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292014000100081&lng=en&tlng=en
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Summary:Objectives: to determine the prevalence of endothelial dysfunction and its association with a history of mild and severe preeclampsia in adolescents. Methods: a cross-sectional study was carried out at the MEAC-UFC with 103 primiparous adolescents postpartum. The assessment of endothelial function was performed by way of flow-mediated dilatation of the brachial artery. Variables (age, body mass index, gestational age at delivery, systolic and diastolic blood pressure and flow-mediated dilation) were compared between groups. p<0.05 was considered to be statistically significant. Results: twenty-four (23.3%) patients had preeclampsia (PE): 11 mild and 13 severe. The overall prevalence of endothelial dysfunction was 23.3% (21.5% of patients with normotensive pregnancies and 29.2% of the PE patients: 18.2% of those with mild PE and 38.5% of those with severe PE). The figures were statistically significant for systolic blood pressure, p=0.007. Conclusions: patients with a history of PE have higher systolic blood pressure than patients with a history of normotensive pregnancy, but did not have more endothelial dysfunction.
ISSN:1806-9304