Diagnostic Value of CT-detected Extramural Vessel Invasion in Lymph Node Metastasis of Gastric Cancer
Objective: To investigate the diagnostic value of extramural vessel invasion (EMVI) in multidetector row computed tomography (MDCT) of lymph node metastasis of gastric cancer. Methods: A total of 105 patients with pathologically confirmed gastric cancer treated at our hospital between January 2020 a...
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| Format: | Article |
| Language: | English |
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Editorial Office of Computerized Tomography Theory and Application
2024-03-01
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| Series: | CT Lilun yu yingyong yanjiu |
| Subjects: | |
| Online Access: | https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2023.005 |
| _version_ | 1827324516351606784 |
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| author | Zhengqi ZHU Shufeng DUAN Haipeng GONG |
| author_facet | Zhengqi ZHU Shufeng DUAN Haipeng GONG |
| author_sort | Zhengqi ZHU |
| collection | DOAJ |
| description | Objective: To investigate the diagnostic value of extramural vessel invasion (EMVI) in multidetector row computed tomography (MDCT) of lymph node metastasis of gastric cancer. Methods: A total of 105 patients with pathologically confirmed gastric cancer treated at our hospital between January 2020 and June 2022 were retrospectively collected. All patients underwent radical gastrectomy and D2 lymph node dissection within 2 weeks after the CT scan. The EMVI status of gastric cancer was evaluated on portal-phase MDCT images using a 5-point scale. According to the pathological status of lymph node metastasis, the patients were divided into lymph node and non-lymph node metastasis groups, and their clinicopathologic features were compared. We then performed a multivariate logistic regression analysis of lymph node metastasis in gastric cancer. A receiver operating characteristic (ROC) curve was used to evaluate the diagnostic value of CT-detected EMVI (ctEMVI) in lymph node metastasis, and the diagnostic values of ctEMVI and lymph node short diameter in lymph node metastasis were compared. Results: In the lymph node metastasis group, lymphovascular invasion, tumor size (>5 cm), ctEMVI positivity, and CT metastatic lymph node positivity accounted for 60.9% (n=39), 64.1% (n=41), 79.7% (n=51), and 56.2% (n=36) of cases, respectively. In the non-metastatic group, lymphovascular invasion, tumor size (>5 cm), ctEMVI positivity, and CT metastatic lymph node positivity accounted for 21.9% (n=9), 24.4% (n=10), 21.9% (n=9), and 19.5% (n=8), respectively. The intergroup difference was statistically significant. The multivariate logistic regression analysis showed that ctEMVI was an independent factor of lymph node metastasis. The ROC curve showed that the area under the curve of ctEMVI for diagnosing lymph node metastasis was 0.854. The sensitivity and accuracy of ctEMVI were superior to those of lymph node short diameter in the diagnosis of lymph node metastasis. Conclusion: This study found that ctEMVI was an independent factor and of great value in the diagnosis of lymph node metastasis. |
| first_indexed | 2024-04-25T02:14:46Z |
| format | Article |
| id | doaj.art-3e9f975ce887426186d9d60a4a9a21f5 |
| institution | Directory Open Access Journal |
| issn | 1004-4140 |
| language | English |
| last_indexed | 2024-04-25T02:14:46Z |
| publishDate | 2024-03-01 |
| publisher | Editorial Office of Computerized Tomography Theory and Application |
| record_format | Article |
| series | CT Lilun yu yingyong yanjiu |
| spelling | doaj.art-3e9f975ce887426186d9d60a4a9a21f52024-03-07T09:42:00ZengEditorial Office of Computerized Tomography Theory and ApplicationCT Lilun yu yingyong yanjiu1004-41402024-03-0133220721210.15953/j.ctta.2023.0052023.005Diagnostic Value of CT-detected Extramural Vessel Invasion in Lymph Node Metastasis of Gastric CancerZhengqi ZHU0Shufeng DUAN1Haipeng GONG2Department of Radiology, Nantong Cancer Hospital, Nantong 226300 ChinaDepartment of Radiology, Nantong Cancer Hospital, Nantong 226300 ChinaDepartment of Radiology, Nantong Cancer Hospital, Nantong 226300 ChinaObjective: To investigate the diagnostic value of extramural vessel invasion (EMVI) in multidetector row computed tomography (MDCT) of lymph node metastasis of gastric cancer. Methods: A total of 105 patients with pathologically confirmed gastric cancer treated at our hospital between January 2020 and June 2022 were retrospectively collected. All patients underwent radical gastrectomy and D2 lymph node dissection within 2 weeks after the CT scan. The EMVI status of gastric cancer was evaluated on portal-phase MDCT images using a 5-point scale. According to the pathological status of lymph node metastasis, the patients were divided into lymph node and non-lymph node metastasis groups, and their clinicopathologic features were compared. We then performed a multivariate logistic regression analysis of lymph node metastasis in gastric cancer. A receiver operating characteristic (ROC) curve was used to evaluate the diagnostic value of CT-detected EMVI (ctEMVI) in lymph node metastasis, and the diagnostic values of ctEMVI and lymph node short diameter in lymph node metastasis were compared. Results: In the lymph node metastasis group, lymphovascular invasion, tumor size (>5 cm), ctEMVI positivity, and CT metastatic lymph node positivity accounted for 60.9% (n=39), 64.1% (n=41), 79.7% (n=51), and 56.2% (n=36) of cases, respectively. In the non-metastatic group, lymphovascular invasion, tumor size (>5 cm), ctEMVI positivity, and CT metastatic lymph node positivity accounted for 21.9% (n=9), 24.4% (n=10), 21.9% (n=9), and 19.5% (n=8), respectively. The intergroup difference was statistically significant. The multivariate logistic regression analysis showed that ctEMVI was an independent factor of lymph node metastasis. The ROC curve showed that the area under the curve of ctEMVI for diagnosing lymph node metastasis was 0.854. The sensitivity and accuracy of ctEMVI were superior to those of lymph node short diameter in the diagnosis of lymph node metastasis. Conclusion: This study found that ctEMVI was an independent factor and of great value in the diagnosis of lymph node metastasis.https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2023.005ctextramural vessel invasiongastric cancerlymph node metastasis |
| spellingShingle | Zhengqi ZHU Shufeng DUAN Haipeng GONG Diagnostic Value of CT-detected Extramural Vessel Invasion in Lymph Node Metastasis of Gastric Cancer CT Lilun yu yingyong yanjiu ct extramural vessel invasion gastric cancer lymph node metastasis |
| title | Diagnostic Value of CT-detected Extramural Vessel Invasion in Lymph Node Metastasis of Gastric Cancer |
| title_full | Diagnostic Value of CT-detected Extramural Vessel Invasion in Lymph Node Metastasis of Gastric Cancer |
| title_fullStr | Diagnostic Value of CT-detected Extramural Vessel Invasion in Lymph Node Metastasis of Gastric Cancer |
| title_full_unstemmed | Diagnostic Value of CT-detected Extramural Vessel Invasion in Lymph Node Metastasis of Gastric Cancer |
| title_short | Diagnostic Value of CT-detected Extramural Vessel Invasion in Lymph Node Metastasis of Gastric Cancer |
| title_sort | diagnostic value of ct detected extramural vessel invasion in lymph node metastasis of gastric cancer |
| topic | ct extramural vessel invasion gastric cancer lymph node metastasis |
| url | https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2023.005 |
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