Low Uptake of the Second Dose of Human Papillomavirus Vaccine in Dar es Salaam, Tanzania
Cervical cancer represents the most common neoplastic pathology among women, with a high burden of morbidity and mortality globally. Tanzania is no exception. The human papillomavirus (HPV) vaccine remains the most effective intervention to address such a burden. However, the uptake of the second do...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/10/11/1919 |
| _version_ | 1797463812983488512 |
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| author | Nchang’wa Nhumba Bruno Sunguya |
| author_facet | Nchang’wa Nhumba Bruno Sunguya |
| author_sort | Nchang’wa Nhumba |
| collection | DOAJ |
| description | Cervical cancer represents the most common neoplastic pathology among women, with a high burden of morbidity and mortality globally. Tanzania is no exception. The human papillomavirus (HPV) vaccine remains the most effective intervention to address such a burden. However, the uptake of the second dose to confer full immunity remains a challenge. This study aimed to assess the uptake and factors associated with the second dose of the HPV (HPV-2) vaccine uptake among adolescents in the Ilala municipality of Dar es Salaam, Tanzania. Using a quantitative cross-sectional study, data of 389 adolescent girls was collected using a self-administered structured questionnaire. Analyses were conducted using Statistical Package for the Social Sciences (SPSS) software through descriptive and multivariate logistic regression methods to determine uptake, characteristics, and factors associated with the uptake of the second dose of the HPV vaccine. Among the 389 adolescents, the uptake of the HPV-2 vaccine dose was only 21.3%, a lower level compared with the first dose of HPV vaccine (35.2%). Factors associated with the uptake of the HPV-2 vaccine were age (AOR 0.14, <i>p</i> = 0.008), positive attitude towards the HPV-2 vaccine (AOR 2.04, <i>p</i> = 0.023), and awareness of the HPV-2 vaccine (AOR: 9.16, <i>p</i> = 0.003). In conclusion, only one in five adolescents in the Ilala municipality received a second dose of HPV vaccine. Such low uptake was associated with attitude towards the HPV vaccine and low awareness of HPV-2 vaccines. Regular community sensitization and awareness campaigns by relevant authorities and implementers may help to increase the HPV vaccine uptake. |
| first_indexed | 2024-03-09T17:56:59Z |
| format | Article |
| id | doaj.art-3ea0a7c7d9b848b0a4ce6945fce1a6c6 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-09T17:56:59Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-3ea0a7c7d9b848b0a4ce6945fce1a6c62023-11-24T10:16:36ZengMDPI AGVaccines2076-393X2022-11-011011191910.3390/vaccines10111919Low Uptake of the Second Dose of Human Papillomavirus Vaccine in Dar es Salaam, TanzaniaNchang’wa Nhumba0Bruno Sunguya1School of Public Health and Social Science, Muhimbili University of Health and Allied Sciences, Dar es Salaam 11103, TanzaniaSchool of Public Health and Social Science, Muhimbili University of Health and Allied Sciences, Dar es Salaam 11103, TanzaniaCervical cancer represents the most common neoplastic pathology among women, with a high burden of morbidity and mortality globally. Tanzania is no exception. The human papillomavirus (HPV) vaccine remains the most effective intervention to address such a burden. However, the uptake of the second dose to confer full immunity remains a challenge. This study aimed to assess the uptake and factors associated with the second dose of the HPV (HPV-2) vaccine uptake among adolescents in the Ilala municipality of Dar es Salaam, Tanzania. Using a quantitative cross-sectional study, data of 389 adolescent girls was collected using a self-administered structured questionnaire. Analyses were conducted using Statistical Package for the Social Sciences (SPSS) software through descriptive and multivariate logistic regression methods to determine uptake, characteristics, and factors associated with the uptake of the second dose of the HPV vaccine. Among the 389 adolescents, the uptake of the HPV-2 vaccine dose was only 21.3%, a lower level compared with the first dose of HPV vaccine (35.2%). Factors associated with the uptake of the HPV-2 vaccine were age (AOR 0.14, <i>p</i> = 0.008), positive attitude towards the HPV-2 vaccine (AOR 2.04, <i>p</i> = 0.023), and awareness of the HPV-2 vaccine (AOR: 9.16, <i>p</i> = 0.003). In conclusion, only one in five adolescents in the Ilala municipality received a second dose of HPV vaccine. Such low uptake was associated with attitude towards the HPV vaccine and low awareness of HPV-2 vaccines. Regular community sensitization and awareness campaigns by relevant authorities and implementers may help to increase the HPV vaccine uptake.https://www.mdpi.com/2076-393X/10/11/1919human papillomavirushuman papillomavirus vaccineuptake of HPV vaccine second doseTanzania |
| spellingShingle | Nchang’wa Nhumba Bruno Sunguya Low Uptake of the Second Dose of Human Papillomavirus Vaccine in Dar es Salaam, Tanzania Vaccines human papillomavirus human papillomavirus vaccine uptake of HPV vaccine second dose Tanzania |
| title | Low Uptake of the Second Dose of Human Papillomavirus Vaccine in Dar es Salaam, Tanzania |
| title_full | Low Uptake of the Second Dose of Human Papillomavirus Vaccine in Dar es Salaam, Tanzania |
| title_fullStr | Low Uptake of the Second Dose of Human Papillomavirus Vaccine in Dar es Salaam, Tanzania |
| title_full_unstemmed | Low Uptake of the Second Dose of Human Papillomavirus Vaccine in Dar es Salaam, Tanzania |
| title_short | Low Uptake of the Second Dose of Human Papillomavirus Vaccine in Dar es Salaam, Tanzania |
| title_sort | low uptake of the second dose of human papillomavirus vaccine in dar es salaam tanzania |
| topic | human papillomavirus human papillomavirus vaccine uptake of HPV vaccine second dose Tanzania |
| url | https://www.mdpi.com/2076-393X/10/11/1919 |
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