Clinical impacts of copy number variations in B-cell differentiation and cell cycle control genes in pediatric B-cell acute lymphoblastic leukemia: a single centre experience

Clinical impacts of copy number variations in B-cell differentiation and cell cycle control genes in pediatric B-cell acute lymphoblastic leukemia: a single centre experience

IKZF1 gene deletions have been identified as a poor prognostic factor in pediatric B-cell acute lymphoblastic leukemia (B-ALL), especially in the presence of co-occurring deletions (IKZF1plus profile). This study aimed to determine the frequency of IKZF1 deletions and deletions in other B-cell diffe...

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Bibliographic Details
Main Authors: Crepinsek Klementina, Marinsek Gasper, Kavcic Marko, Prelog Tomaž, Kitanovski Lidija, Jazbec Janez, Debeljak Marusa
Format: Article
Language:English
Published: Sciendo 2021-12-01
Series:Radiology and Oncology
Subjects:
b-acute lymphoblastic leukemia
ikzf1 deletions
ikzf1plus
mlpa
pediatric
copy number variations (cnvs)
Online Access:https://doi.org/10.2478/raon-2021-0050

Internet

https://doi.org/10.2478/raon-2021-0050

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