Chitosan-Based Composite Materials for Prospective Hemostatic Applications

Effective hemostasis is vital to reduce the pain and mortality of patients, and the research and development of hemostatic materials are prerequisite for effective hemostasis. Chitosan (CS), with good biodegradability, biocompatibility and non-toxicity, has been widely applied in bio-medicine, the c...

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Main Authors: Zhang Hu, Dong-Ying Zhang, Si-Tong Lu, Pu-Wang Li, Si-Dong Li
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/16/8/273
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author Zhang Hu
Dong-Ying Zhang
Si-Tong Lu
Pu-Wang Li
Si-Dong Li
author_facet Zhang Hu
Dong-Ying Zhang
Si-Tong Lu
Pu-Wang Li
Si-Dong Li
author_sort Zhang Hu
collection DOAJ
description Effective hemostasis is vital to reduce the pain and mortality of patients, and the research and development of hemostatic materials are prerequisite for effective hemostasis. Chitosan (CS), with good biodegradability, biocompatibility and non-toxicity, has been widely applied in bio-medicine, the chemical industry, the food industry and cosmetics. The excellent hemostatic properties of CS have been extensively studied. As a result, chitosan-based composite hemostatic materials have been emerging. In this review, the hemostatic mechanism of chitosan is briefly discussed, and then the progress of research on chitosan-based composite hemostatic materials with multiple forms such as films, sponges, hydrogels, particles and fibers are introduced. Finally, future perspectives of chitosan-based composite hemostatic materials are given. The objective of this review is to provide a reference for further research and development of effective hemostatic materials.
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spelling doaj.art-3ea660af29a549c68d1b98a023afcd862022-12-22T02:53:03ZengMDPI AGMarine Drugs1660-33972018-08-0116827310.3390/md16080273md16080273Chitosan-Based Composite Materials for Prospective Hemostatic ApplicationsZhang Hu0Dong-Ying Zhang1Si-Tong Lu2Pu-Wang Li3Si-Dong Li4Department of Applied Chemistry, School of Chemistry and Environmental Science, Guangdong Ocean University, Zhanjiang 524088, Guangdong, ChinaDepartment of Applied Chemistry, School of Chemistry and Environmental Science, Guangdong Ocean University, Zhanjiang 524088, Guangdong, ChinaDepartment of Applied Chemistry, School of Chemistry and Environmental Science, Guangdong Ocean University, Zhanjiang 524088, Guangdong, ChinaAgricultural Product Processing Research Institute, Chinese Academy of Tropical Agricultural Sciences, Zhanjiang 524001, Guangdong, ChinaDepartment of Applied Chemistry, School of Chemistry and Environmental Science, Guangdong Ocean University, Zhanjiang 524088, Guangdong, ChinaEffective hemostasis is vital to reduce the pain and mortality of patients, and the research and development of hemostatic materials are prerequisite for effective hemostasis. Chitosan (CS), with good biodegradability, biocompatibility and non-toxicity, has been widely applied in bio-medicine, the chemical industry, the food industry and cosmetics. The excellent hemostatic properties of CS have been extensively studied. As a result, chitosan-based composite hemostatic materials have been emerging. In this review, the hemostatic mechanism of chitosan is briefly discussed, and then the progress of research on chitosan-based composite hemostatic materials with multiple forms such as films, sponges, hydrogels, particles and fibers are introduced. Finally, future perspectives of chitosan-based composite hemostatic materials are given. The objective of this review is to provide a reference for further research and development of effective hemostatic materials.http://www.mdpi.com/1660-3397/16/8/273chitosancomposite materialshemostasismechanismsfilmsspongeshydrogelsparticlesfibersapplications
spellingShingle Zhang Hu
Dong-Ying Zhang
Si-Tong Lu
Pu-Wang Li
Si-Dong Li
Chitosan-Based Composite Materials for Prospective Hemostatic Applications
Marine Drugs
chitosan
composite materials
hemostasis
mechanisms
films
sponges
hydrogels
particles
fibers
applications
title Chitosan-Based Composite Materials for Prospective Hemostatic Applications
title_full Chitosan-Based Composite Materials for Prospective Hemostatic Applications
title_fullStr Chitosan-Based Composite Materials for Prospective Hemostatic Applications
title_full_unstemmed Chitosan-Based Composite Materials for Prospective Hemostatic Applications
title_short Chitosan-Based Composite Materials for Prospective Hemostatic Applications
title_sort chitosan based composite materials for prospective hemostatic applications
topic chitosan
composite materials
hemostasis
mechanisms
films
sponges
hydrogels
particles
fibers
applications
url http://www.mdpi.com/1660-3397/16/8/273
work_keys_str_mv AT zhanghu chitosanbasedcompositematerialsforprospectivehemostaticapplications
AT dongyingzhang chitosanbasedcompositematerialsforprospectivehemostaticapplications
AT sitonglu chitosanbasedcompositematerialsforprospectivehemostaticapplications
AT puwangli chitosanbasedcompositematerialsforprospectivehemostaticapplications
AT sidongli chitosanbasedcompositematerialsforprospectivehemostaticapplications