Reactive astrogliosis in the era of single-cell transcriptomics

Reactive astrogliosis in the era of single-cell transcriptomics

Reactive astrogliosis is a reaction of astrocytes to disturbed homeostasis in the central nervous system (CNS), accompanied by changes in astrocyte numbers, morphology, and function. Reactive astrocytes are important in the onset and progression of many neuropathologies, such as neurotrauma, stroke,...

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Bibliographic Details
Main Authors: Zuzana Matusova, Elly M. Hol, Milos Pekny, Mikael Kubista, Lukas Valihrach
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
reactive astrogliosis
astrocytes
cell populations
single-cell RNA-seq
neuroinflammation
neurodegeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1173200/full

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