A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing Surgery
BackgroundWhen we treat renal cell carcinoma by laparoscopic nephron-sparing surgery (NSS), it is essential to use an evaluation system to predict clinical outcomes. Hitherto, there are more than a dozen nephrometry score systems. In this study, through assessing the correlations between nephrometry...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.922082/full |
| _version_ | 1811292285706436608 |
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| author | Shudong Zhang Zijian Qin Hai Bi Liyuan Tao Fan Zhang Hongxian Zhang Wei Wang Jitao Wu Yi Huang Lulin Ma |
| author_facet | Shudong Zhang Zijian Qin Hai Bi Liyuan Tao Fan Zhang Hongxian Zhang Wei Wang Jitao Wu Yi Huang Lulin Ma |
| author_sort | Shudong Zhang |
| collection | DOAJ |
| description | BackgroundWhen we treat renal cell carcinoma by laparoscopic nephron-sparing surgery (NSS), it is essential to use an evaluation system to predict clinical outcomes. Hitherto, there are more than a dozen nephrometry score systems. In this study, through assessing the correlations between nephrometry score systems and clinical outcomes, we aim to provide a novel nephrometry score system—the “3S+f” score system—to simplify the evaluation of technical complexity of partial nephrectomy.MethodsWe retrospectively collected the data of 131 patients who underwent NSS, which was performed by a single surgeon (SZ) from January 2013 to July 2018 at Peking University Third Hospital. The “3S+f” score system contains four parameters: “size, side, site, and fat”, all of which can be obtained from preoperative imaging data. We evaluated the correlations between the “3S+f” score and clinical outcomes, and compared R.E.N.A.L. score and PADUA score.ResultsAll the three nephrometry score systems were related to some clinical outcomes in univariate analyses. In multivariate regression models, the “3S+f” score, the R.E.N.A.L. score, and the PADUA score were significantly associated with operative time (p = 0.016, p = 0.035, and p = 0.001, respectively) and warm ischemia time (all p = 0.008, p < 0.001, and p < 0.001, respectively). “3S+f” was also significantly related to extubation time > 5 days (p = 0.018). In predicting operative time > 120 min and extubation time >5 days from ROC curves, the AUCs of the “3S+f” score (0.717 and 0.652, respectively) were larger than both the R.E.N.A.L (0.598 and 0.554, respectively) and PADUA (0.600 and 0.542, respectively) score systems.ConclusionA novel nephrometry score system—the “3S+f” score system—shows equivalent correlation and the ability in predicting clinical outcomes when compared to the R.E.N.A.L. score system and the PADUA score system, which can describe renal tumors. |
| first_indexed | 2024-04-13T04:43:08Z |
| format | Article |
| id | doaj.art-3ea6a5bcd4be4666b35220480e546c01 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-13T04:43:08Z |
| publishDate | 2022-07-01 |
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| series | Frontiers in Oncology |
| spelling | doaj.art-3ea6a5bcd4be4666b35220480e546c012022-12-22T03:01:55ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2022-07-011210.3389/fonc.2022.922082922082A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing SurgeryShudong Zhang0Zijian Qin1Hai Bi2Liyuan Tao3Fan Zhang4Hongxian Zhang5Wei Wang6Jitao Wu7Yi Huang8Lulin Ma9Department of Urology, Peking University Third Hospital, Peking University, Beijing, ChinaDepartment of Urology, Peking University Third Hospital, Peking University, Beijing, ChinaDepartment of Urology, Peking University Third Hospital, Peking University, Beijing, ChinaDepartment of Epidemiology, Peking University Third Hospital, Peking University, Beijing, ChinaDepartment of Urology, Peking University Third Hospital, Peking University, Beijing, ChinaDepartment of Urology, Peking University Third Hospital, Peking University, Beijing, ChinaDepartment of Urology, Peking Tongren Hospital, Beijing, ChinaDepartment of Urology, Yantai Yuhuangding Hospital, Yantai, ChinaDepartment of Urology, Peking University Third Hospital, Peking University, Beijing, ChinaDepartment of Urology, Peking University Third Hospital, Peking University, Beijing, ChinaBackgroundWhen we treat renal cell carcinoma by laparoscopic nephron-sparing surgery (NSS), it is essential to use an evaluation system to predict clinical outcomes. Hitherto, there are more than a dozen nephrometry score systems. In this study, through assessing the correlations between nephrometry score systems and clinical outcomes, we aim to provide a novel nephrometry score system—the “3S+f” score system—to simplify the evaluation of technical complexity of partial nephrectomy.MethodsWe retrospectively collected the data of 131 patients who underwent NSS, which was performed by a single surgeon (SZ) from January 2013 to July 2018 at Peking University Third Hospital. The “3S+f” score system contains four parameters: “size, side, site, and fat”, all of which can be obtained from preoperative imaging data. We evaluated the correlations between the “3S+f” score and clinical outcomes, and compared R.E.N.A.L. score and PADUA score.ResultsAll the three nephrometry score systems were related to some clinical outcomes in univariate analyses. In multivariate regression models, the “3S+f” score, the R.E.N.A.L. score, and the PADUA score were significantly associated with operative time (p = 0.016, p = 0.035, and p = 0.001, respectively) and warm ischemia time (all p = 0.008, p < 0.001, and p < 0.001, respectively). “3S+f” was also significantly related to extubation time > 5 days (p = 0.018). In predicting operative time > 120 min and extubation time >5 days from ROC curves, the AUCs of the “3S+f” score (0.717 and 0.652, respectively) were larger than both the R.E.N.A.L (0.598 and 0.554, respectively) and PADUA (0.600 and 0.542, respectively) score systems.ConclusionA novel nephrometry score system—the “3S+f” score system—shows equivalent correlation and the ability in predicting clinical outcomes when compared to the R.E.N.A.L. score system and the PADUA score system, which can describe renal tumors.https://www.frontiersin.org/articles/10.3389/fonc.2022.922082/fullnephrometry score systemrenal tumorlaparoscopynephron-sparing surgery“3S+f” nephrometry score system |
| spellingShingle | Shudong Zhang Zijian Qin Hai Bi Liyuan Tao Fan Zhang Hongxian Zhang Wei Wang Jitao Wu Yi Huang Lulin Ma A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing Surgery Frontiers in Oncology nephrometry score system renal tumor laparoscopy nephron-sparing surgery “3S+f” nephrometry score system |
| title | A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing Surgery |
| title_full | A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing Surgery |
| title_fullStr | A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing Surgery |
| title_full_unstemmed | A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing Surgery |
| title_short | A “3S+f” Nephrometry Score System to Predict the Clinical Outcomes of Laparoscopic Nephron-Sparing Surgery |
| title_sort | 3s f nephrometry score system to predict the clinical outcomes of laparoscopic nephron sparing surgery |
| topic | nephrometry score system renal tumor laparoscopy nephron-sparing surgery “3S+f” nephrometry score system |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2022.922082/full |
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