Post-ST-Segment Elevation Myocardial Infarction Follow-Up Care During the COVID-19 Pandemic and the Possible Benefit of Telemedicine: An Observational Study

Background: Infectious control measures during the COVID-19 pandemic have led to the propensity toward telemedicine. This study examined the impact of telemedicine during the pandemic on the long-term outcomes of ST-segment elevation myocardial infarction (STEMI) patients.Methods: This study include...

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Main Authors: Audrey A. Y. Zhang, Nicholas W. S. Chew, Cheng Han Ng, Kailun Phua, Yin Nwe Aye, Aaron Mai, Gwyneth Kong, Kalyar Saw, Raymond C. C. Wong, William K. F. Kong, Kian-Keong Poh, Koo-Hui Chan, Adrian Fatt-Hoe Low, Chi-Hang Lee, Mark Yan-Yee Chan, Ping Chai, James Yip, Tiong-Cheng Yeo, Huay-Cheem Tan, Poay-Huan Loh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.755822/full
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author Audrey A. Y. Zhang
Nicholas W. S. Chew
Cheng Han Ng
Kailun Phua
Yin Nwe Aye
Aaron Mai
Gwyneth Kong
Kalyar Saw
Raymond C. C. Wong
Raymond C. C. Wong
William K. F. Kong
William K. F. Kong
Kian-Keong Poh
Kian-Keong Poh
Koo-Hui Chan
Koo-Hui Chan
Adrian Fatt-Hoe Low
Adrian Fatt-Hoe Low
Chi-Hang Lee
Chi-Hang Lee
Mark Yan-Yee Chan
Mark Yan-Yee Chan
Ping Chai
Ping Chai
James Yip
James Yip
Tiong-Cheng Yeo
Tiong-Cheng Yeo
Huay-Cheem Tan
Huay-Cheem Tan
Poay-Huan Loh
Poay-Huan Loh
author_facet Audrey A. Y. Zhang
Nicholas W. S. Chew
Cheng Han Ng
Kailun Phua
Yin Nwe Aye
Aaron Mai
Gwyneth Kong
Kalyar Saw
Raymond C. C. Wong
Raymond C. C. Wong
William K. F. Kong
William K. F. Kong
Kian-Keong Poh
Kian-Keong Poh
Koo-Hui Chan
Koo-Hui Chan
Adrian Fatt-Hoe Low
Adrian Fatt-Hoe Low
Chi-Hang Lee
Chi-Hang Lee
Mark Yan-Yee Chan
Mark Yan-Yee Chan
Ping Chai
Ping Chai
James Yip
James Yip
Tiong-Cheng Yeo
Tiong-Cheng Yeo
Huay-Cheem Tan
Huay-Cheem Tan
Poay-Huan Loh
Poay-Huan Loh
author_sort Audrey A. Y. Zhang
collection DOAJ
description Background: Infectious control measures during the COVID-19 pandemic have led to the propensity toward telemedicine. This study examined the impact of telemedicine during the pandemic on the long-term outcomes of ST-segment elevation myocardial infarction (STEMI) patients.Methods: This study included 288 patients admitted 1 year before the pandemic (October 2018–December 2018) and during the pandemic (January 2020–March 2020) eras, and survived their index STEMI admission. The follow-up period was 1 year. One-year primary safety endpoint was all-cause mortality. Secondary safety endpoints were cardiac readmissions for unplanned revascularisation, non-fatal myocardial infarction, heart failure, arrythmia, unstable angina. Major adverse cardiovascular events (MACE) was defined as the composite outcome of each individual safety endpoint.Results: Despite unfavorable in-hospital outcomes among patients admitted during the pandemic compared to pre-pandemic era, both groups had similar 1-year all-cause mortality (11.2 vs. 8.5%, respectively, p = 0.454) but higher cardiac-related (14.1 vs. 5.1%, p < 0.001) and heart failure readmissions in the pandemic vs. pre-pandemic groups (7.1 vs. 1.7%, p = 0.037). Follow-up was more frequently conducted via teleconsultations (1.2 vs. 0.2 per patient/year, p = 0.001), with reduction in physical consultations (2.1 vs. 2.6 per patient/year, p = 0.043), during the pandemic vs. pre-pandemic era. Majority achieved guideline-directed medical therapy (GDMT) during pandemic vs. pre-pandemic era (75.9 vs. 61.6%, p = 0.010). Multivariable Cox regression demonstrated achieving medication target doses (HR 0.387, 95% CI 0.164–0.915, p = 0.031) and GDMT (HR 0.271, 95% CI 0.134–0.548, p < 0.001) were independent predictors of lower 1-year MACE after adjustment.Conclusion: The pandemic has led to the wider application of teleconsultation, with increased adherence to GDMT, enhanced medication target dosing. Achieving GDMT was associated with favorable long-term prognosis.
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spelling doaj.art-3ea88d4e421c4581bab27566f3b606022022-12-21T21:56:48ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2021-10-01810.3389/fcvm.2021.755822755822Post-ST-Segment Elevation Myocardial Infarction Follow-Up Care During the COVID-19 Pandemic and the Possible Benefit of Telemedicine: An Observational StudyAudrey A. Y. Zhang0Nicholas W. S. Chew1Cheng Han Ng2Kailun Phua3Yin Nwe Aye4Aaron Mai5Gwyneth Kong6Kalyar Saw7Raymond C. C. Wong8Raymond C. C. Wong9William K. F. Kong10William K. F. Kong11Kian-Keong Poh12Kian-Keong Poh13Koo-Hui Chan14Koo-Hui Chan15Adrian Fatt-Hoe Low16Adrian Fatt-Hoe Low17Chi-Hang Lee18Chi-Hang Lee19Mark Yan-Yee Chan20Mark Yan-Yee Chan21Ping Chai22Ping Chai23James Yip24James Yip25Tiong-Cheng Yeo26Tiong-Cheng Yeo27Huay-Cheem Tan28Huay-Cheem Tan29Poay-Huan Loh30Poay-Huan Loh31Department of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Medicine, National University Hospital, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeDepartment of Cardiology, National University Heart Centre, National University Health System, Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, Singapore, SingaporeBackground: Infectious control measures during the COVID-19 pandemic have led to the propensity toward telemedicine. This study examined the impact of telemedicine during the pandemic on the long-term outcomes of ST-segment elevation myocardial infarction (STEMI) patients.Methods: This study included 288 patients admitted 1 year before the pandemic (October 2018–December 2018) and during the pandemic (January 2020–March 2020) eras, and survived their index STEMI admission. The follow-up period was 1 year. One-year primary safety endpoint was all-cause mortality. Secondary safety endpoints were cardiac readmissions for unplanned revascularisation, non-fatal myocardial infarction, heart failure, arrythmia, unstable angina. Major adverse cardiovascular events (MACE) was defined as the composite outcome of each individual safety endpoint.Results: Despite unfavorable in-hospital outcomes among patients admitted during the pandemic compared to pre-pandemic era, both groups had similar 1-year all-cause mortality (11.2 vs. 8.5%, respectively, p = 0.454) but higher cardiac-related (14.1 vs. 5.1%, p < 0.001) and heart failure readmissions in the pandemic vs. pre-pandemic groups (7.1 vs. 1.7%, p = 0.037). Follow-up was more frequently conducted via teleconsultations (1.2 vs. 0.2 per patient/year, p = 0.001), with reduction in physical consultations (2.1 vs. 2.6 per patient/year, p = 0.043), during the pandemic vs. pre-pandemic era. Majority achieved guideline-directed medical therapy (GDMT) during pandemic vs. pre-pandemic era (75.9 vs. 61.6%, p = 0.010). Multivariable Cox regression demonstrated achieving medication target doses (HR 0.387, 95% CI 0.164–0.915, p = 0.031) and GDMT (HR 0.271, 95% CI 0.134–0.548, p < 0.001) were independent predictors of lower 1-year MACE after adjustment.Conclusion: The pandemic has led to the wider application of teleconsultation, with increased adherence to GDMT, enhanced medication target dosing. Achieving GDMT was associated with favorable long-term prognosis.https://www.frontiersin.org/articles/10.3389/fcvm.2021.755822/fullCOVID-19telemedicinetelehealthST-segment elevation myocardial infarctionpandemic
spellingShingle Audrey A. Y. Zhang
Nicholas W. S. Chew
Cheng Han Ng
Kailun Phua
Yin Nwe Aye
Aaron Mai
Gwyneth Kong
Kalyar Saw
Raymond C. C. Wong
Raymond C. C. Wong
William K. F. Kong
William K. F. Kong
Kian-Keong Poh
Kian-Keong Poh
Koo-Hui Chan
Koo-Hui Chan
Adrian Fatt-Hoe Low
Adrian Fatt-Hoe Low
Chi-Hang Lee
Chi-Hang Lee
Mark Yan-Yee Chan
Mark Yan-Yee Chan
Ping Chai
Ping Chai
James Yip
James Yip
Tiong-Cheng Yeo
Tiong-Cheng Yeo
Huay-Cheem Tan
Huay-Cheem Tan
Poay-Huan Loh
Poay-Huan Loh
Post-ST-Segment Elevation Myocardial Infarction Follow-Up Care During the COVID-19 Pandemic and the Possible Benefit of Telemedicine: An Observational Study
Frontiers in Cardiovascular Medicine
COVID-19
telemedicine
telehealth
ST-segment elevation myocardial infarction
pandemic
title Post-ST-Segment Elevation Myocardial Infarction Follow-Up Care During the COVID-19 Pandemic and the Possible Benefit of Telemedicine: An Observational Study
title_full Post-ST-Segment Elevation Myocardial Infarction Follow-Up Care During the COVID-19 Pandemic and the Possible Benefit of Telemedicine: An Observational Study
title_fullStr Post-ST-Segment Elevation Myocardial Infarction Follow-Up Care During the COVID-19 Pandemic and the Possible Benefit of Telemedicine: An Observational Study
title_full_unstemmed Post-ST-Segment Elevation Myocardial Infarction Follow-Up Care During the COVID-19 Pandemic and the Possible Benefit of Telemedicine: An Observational Study
title_short Post-ST-Segment Elevation Myocardial Infarction Follow-Up Care During the COVID-19 Pandemic and the Possible Benefit of Telemedicine: An Observational Study
title_sort post st segment elevation myocardial infarction follow up care during the covid 19 pandemic and the possible benefit of telemedicine an observational study
topic COVID-19
telemedicine
telehealth
ST-segment elevation myocardial infarction
pandemic
url https://www.frontiersin.org/articles/10.3389/fcvm.2021.755822/full
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