Nanobiomaterials: exploring mechanistic roles in combating microbial infections and cancer

Abstract The initiation of the "nanotechnology era" within the past decade has been prominently marked by advancements in biomaterials. This intersection has opened up numerous possibilities for enhancing the detection, diagnosis, and treatment of various illnesses by leveraging the synerg...

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Main Authors: Neha Rawat, Nabeel Ahmad, Pratishtha Raturi, Nirjara Singhvi, Nitin Sahai, Preeti Kothiyal
Format: Article
Language:English
Published: Springer 2023-12-01
Series:Discover Nano
Subjects:
Online Access:https://doi.org/10.1186/s11671-023-03946-x
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author Neha Rawat
Nabeel Ahmad
Pratishtha Raturi
Nirjara Singhvi
Nitin Sahai
Preeti Kothiyal
author_facet Neha Rawat
Nabeel Ahmad
Pratishtha Raturi
Nirjara Singhvi
Nitin Sahai
Preeti Kothiyal
author_sort Neha Rawat
collection DOAJ
description Abstract The initiation of the "nanotechnology era" within the past decade has been prominently marked by advancements in biomaterials. This intersection has opened up numerous possibilities for enhancing the detection, diagnosis, and treatment of various illnesses by leveraging the synergy between biomaterials and nanotechnology. The term "nano biomaterials" referring to biomaterials featuring constituent or surface feature sizes below 100 nm, presents a realm of extraordinary materials endowed with unique structures and properties. Beyond addressing common biomedical challenges, these nano biomaterials contribute unprecedented insights and principles that enrich our understanding of biology, medicine, and materials science. A critical evaluation of recent technological progress in employing biomaterials in medicine is essential, along with an exploration of potential future trends. Nanotechnology breakthroughs have yielded novel surfaces, materials, and configurations with notable applications in the biomedical domain. The integration of nanotechnology has already begun to enhance traditional biomedical practices across diverse fields such as tissue engineering, intelligent systems, the utilization of nanocomposites in implant design, controlled release systems, biosensors, and more. This mini review encapsulates insights into biomaterials, encompassing their types, synthesis methods, and the roles of organic and inorganic nanoparticles, elucidating their mechanisms of action. Furthermore, the focus is squarely placed on nano biomaterials and their versatile applications, with a particular emphasis on their roles in anticancer and antimicrobial interventions. This review underscores the dynamic landscape of nanotechnology, envisioning a future where nano biomaterials play a pivotal role in advancing medical applications, particularly in combating cancer and microbial infections.
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spelling doaj.art-3eaaa64d6e394847b6dba6ff4e4913e62023-12-24T12:27:01ZengSpringerDiscover Nano2731-92292023-12-0118111510.1186/s11671-023-03946-xNanobiomaterials: exploring mechanistic roles in combating microbial infections and cancerNeha Rawat0Nabeel Ahmad1Pratishtha Raturi2Nirjara Singhvi3Nitin Sahai4Preeti Kothiyal5School of Allied Sciences, Dev Bhoomi Uttarakhand UniversitySchool of Allied Sciences, Dev Bhoomi Uttarakhand UniversitySchool of Allied Sciences, Dev Bhoomi Uttarakhand UniversitySchool of Allied Sciences, Dev Bhoomi Uttarakhand University3D Printing and Visualization Center, University of PecsSchool of Pharmacy and Research, Dev Bhoomi Uttarakhand UniversityAbstract The initiation of the "nanotechnology era" within the past decade has been prominently marked by advancements in biomaterials. This intersection has opened up numerous possibilities for enhancing the detection, diagnosis, and treatment of various illnesses by leveraging the synergy between biomaterials and nanotechnology. The term "nano biomaterials" referring to biomaterials featuring constituent or surface feature sizes below 100 nm, presents a realm of extraordinary materials endowed with unique structures and properties. Beyond addressing common biomedical challenges, these nano biomaterials contribute unprecedented insights and principles that enrich our understanding of biology, medicine, and materials science. A critical evaluation of recent technological progress in employing biomaterials in medicine is essential, along with an exploration of potential future trends. Nanotechnology breakthroughs have yielded novel surfaces, materials, and configurations with notable applications in the biomedical domain. The integration of nanotechnology has already begun to enhance traditional biomedical practices across diverse fields such as tissue engineering, intelligent systems, the utilization of nanocomposites in implant design, controlled release systems, biosensors, and more. This mini review encapsulates insights into biomaterials, encompassing their types, synthesis methods, and the roles of organic and inorganic nanoparticles, elucidating their mechanisms of action. Furthermore, the focus is squarely placed on nano biomaterials and their versatile applications, with a particular emphasis on their roles in anticancer and antimicrobial interventions. This review underscores the dynamic landscape of nanotechnology, envisioning a future where nano biomaterials play a pivotal role in advancing medical applications, particularly in combating cancer and microbial infections.https://doi.org/10.1186/s11671-023-03946-xBiomaterialsNano biomaterialsSynthesisMechanism of actionApplicationsAnticancer
spellingShingle Neha Rawat
Nabeel Ahmad
Pratishtha Raturi
Nirjara Singhvi
Nitin Sahai
Preeti Kothiyal
Nanobiomaterials: exploring mechanistic roles in combating microbial infections and cancer
Discover Nano
Biomaterials
Nano biomaterials
Synthesis
Mechanism of action
Applications
Anticancer
title Nanobiomaterials: exploring mechanistic roles in combating microbial infections and cancer
title_full Nanobiomaterials: exploring mechanistic roles in combating microbial infections and cancer
title_fullStr Nanobiomaterials: exploring mechanistic roles in combating microbial infections and cancer
title_full_unstemmed Nanobiomaterials: exploring mechanistic roles in combating microbial infections and cancer
title_short Nanobiomaterials: exploring mechanistic roles in combating microbial infections and cancer
title_sort nanobiomaterials exploring mechanistic roles in combating microbial infections and cancer
topic Biomaterials
Nano biomaterials
Synthesis
Mechanism of action
Applications
Anticancer
url https://doi.org/10.1186/s11671-023-03946-x
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AT nirjarasinghvi nanobiomaterialsexploringmechanisticrolesincombatingmicrobialinfectionsandcancer
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