Chinese Xibe population genetic composition according to linkage groups of X-chromosomal STRs: population genetic variability and interpopulation comparisons
Background: The Xibe population is one of China’s officially recognised populations and is now distributed separately from west to east in the northern part of China. X-chromosomal short tandem repeats have a special inheritance pattern, and could be used as complements in forensic application, espe...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2017-08-01
|
| Series: | Annals of Human Biology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/03014460.2017.1318951 |
| _version_ | 1827818378120658944 |
|---|---|
| author | Hao-Tian Meng Chun-Mei Shen Yu-Dang Zhang Qian Dong Yu-Xin Guo Guang Yang Jiang-Wei Yan Yao-Shun Liu Ting Mei Jian-Feng Shi Bo-Feng Zhu |
| author_facet | Hao-Tian Meng Chun-Mei Shen Yu-Dang Zhang Qian Dong Yu-Xin Guo Guang Yang Jiang-Wei Yan Yao-Shun Liu Ting Mei Jian-Feng Shi Bo-Feng Zhu |
| author_sort | Hao-Tian Meng |
| collection | DOAJ |
| description | Background: The Xibe population is one of China’s officially recognised populations and is now distributed separately from west to east in the northern part of China. X-chromosomal short tandem repeats have a special inheritance pattern, and could be used as complements in forensic application, especially for complex or deficiency cases. Subjects and methods: This study obtained the allelic and haplotypic frequencies of 19 X-STR loci in the Xibe population from Xinjiang Uygur Autonomous Region, China, and studied the genetic differentiations between the Xibe and other populations. Results: The combined power of discrimination in females and males and mean exclusion chances in deficiency cases, normal trios and duo cases was at least 0.999 999 994. In the haplotypic study, the Xibe population showed a more similar pattern of haplotype distribution with Asian populations than populations from other continents, while allelic study also indicated a closer relationship between the Xibe and Asian populations. Conclusions: The 19 X-STR loci would be useful in forensic application in the studied population. The Xibe population showed a closer genetic relationship with Asian populations in the study, and more population data would be necessary for more detailed genetic relationship studies. |
| first_indexed | 2024-03-12T00:46:54Z |
| format | Article |
| id | doaj.art-3eaaba38b48043c0bacfb161d6c5f033 |
| institution | Directory Open Access Journal |
| issn | 0301-4460 1464-5033 |
| language | English |
| last_indexed | 2024-03-12T00:46:54Z |
| publishDate | 2017-08-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Human Biology |
| spelling | doaj.art-3eaaba38b48043c0bacfb161d6c5f0332023-09-14T15:36:08ZengTaylor & Francis GroupAnnals of Human Biology0301-44601464-50332017-08-0144654655310.1080/03014460.2017.13189511318951Chinese Xibe population genetic composition according to linkage groups of X-chromosomal STRs: population genetic variability and interpopulation comparisonsHao-Tian Meng0Chun-Mei Shen1Yu-Dang Zhang2Qian Dong3Yu-Xin Guo4Guang Yang5Jiang-Wei Yan6Yao-Shun Liu7Ting Mei8Jian-Feng Shi9Bo-Feng Zhu10Xi’an Jiaotong UniversityBlood Center of Shaanxi ProvinceXi’an Jiaotong UniversityXi’an Jiaotong UniversityXi’an Jiaotong UniversityLaboratory of Medicine, Loma Linda University Medical CenterBeijing Institute of Genomics, Chinese Academy of SciencesPreclinical Medicine College, Xinjiang Medical UniversityPreclinical Medicine College, Xinjiang Medical UniversityXi’an Jiaotong UniversityXi’an Jiaotong UniversityBackground: The Xibe population is one of China’s officially recognised populations and is now distributed separately from west to east in the northern part of China. X-chromosomal short tandem repeats have a special inheritance pattern, and could be used as complements in forensic application, especially for complex or deficiency cases. Subjects and methods: This study obtained the allelic and haplotypic frequencies of 19 X-STR loci in the Xibe population from Xinjiang Uygur Autonomous Region, China, and studied the genetic differentiations between the Xibe and other populations. Results: The combined power of discrimination in females and males and mean exclusion chances in deficiency cases, normal trios and duo cases was at least 0.999 999 994. In the haplotypic study, the Xibe population showed a more similar pattern of haplotype distribution with Asian populations than populations from other continents, while allelic study also indicated a closer relationship between the Xibe and Asian populations. Conclusions: The 19 X-STR loci would be useful in forensic application in the studied population. The Xibe population showed a closer genetic relationship with Asian populations in the study, and more population data would be necessary for more detailed genetic relationship studies.http://dx.doi.org/10.1080/03014460.2017.1318951xibe populationx-strinterpopulation comparisonhaplotype diversitypopulation data |
| spellingShingle | Hao-Tian Meng Chun-Mei Shen Yu-Dang Zhang Qian Dong Yu-Xin Guo Guang Yang Jiang-Wei Yan Yao-Shun Liu Ting Mei Jian-Feng Shi Bo-Feng Zhu Chinese Xibe population genetic composition according to linkage groups of X-chromosomal STRs: population genetic variability and interpopulation comparisons Annals of Human Biology xibe population x-str interpopulation comparison haplotype diversity population data |
| title | Chinese Xibe population genetic composition according to linkage groups of X-chromosomal STRs: population genetic variability and interpopulation comparisons |
| title_full | Chinese Xibe population genetic composition according to linkage groups of X-chromosomal STRs: population genetic variability and interpopulation comparisons |
| title_fullStr | Chinese Xibe population genetic composition according to linkage groups of X-chromosomal STRs: population genetic variability and interpopulation comparisons |
| title_full_unstemmed | Chinese Xibe population genetic composition according to linkage groups of X-chromosomal STRs: population genetic variability and interpopulation comparisons |
| title_short | Chinese Xibe population genetic composition according to linkage groups of X-chromosomal STRs: population genetic variability and interpopulation comparisons |
| title_sort | chinese xibe population genetic composition according to linkage groups of x chromosomal strs population genetic variability and interpopulation comparisons |
| topic | xibe population x-str interpopulation comparison haplotype diversity population data |
| url | http://dx.doi.org/10.1080/03014460.2017.1318951 |
| work_keys_str_mv | AT haotianmeng chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons AT chunmeishen chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons AT yudangzhang chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons AT qiandong chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons AT yuxinguo chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons AT guangyang chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons AT jiangweiyan chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons AT yaoshunliu chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons AT tingmei chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons AT jianfengshi chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons AT bofengzhu chinesexibepopulationgeneticcompositionaccordingtolinkagegroupsofxchromosomalstrspopulationgeneticvariabilityandinterpopulationcomparisons |