Computational wave-based photoacoustic imaging through an unknown thick aberrating layer

We introduce a physics-based computational reconstruction framework for non-invasive photoacoustic tomography through a thick aberrating layer. Our wave-based approach leverages an analytic formulation of diffraction to beamform a photoacoustic image, when the aberrating layer profile is known. When...

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Main Authors: Yevgeny Slobodkin, Ori Katz
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Photoacoustics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213597924000016
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author Yevgeny Slobodkin
Ori Katz
author_facet Yevgeny Slobodkin
Ori Katz
author_sort Yevgeny Slobodkin
collection DOAJ
description We introduce a physics-based computational reconstruction framework for non-invasive photoacoustic tomography through a thick aberrating layer. Our wave-based approach leverages an analytic formulation of diffraction to beamform a photoacoustic image, when the aberrating layer profile is known. When the profile of the aberrating layer is unknown, the same analytical formulation serves as the basis for an automatic-differentiation regularized optimization algorithm that simultaneously reconstructs both the profile of the aberrating layer and the optically absorbing targets. Results from numerical studies and proof-of-concept experiments show promise for fast beamforming that takes into account diffraction effects occurring in the propagation through thick, highly-aberrating layers.
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spelling doaj.art-3ead09cc3eb24c12b7df7d7ac43fd16a2024-02-22T04:52:32ZengElsevierPhotoacoustics2213-59792024-04-0136100584Computational wave-based photoacoustic imaging through an unknown thick aberrating layerYevgeny Slobodkin0Ori Katz1Institute of Applied Physics, The Hebrew University of Jerusalem, Jerusalem 9190401, IsraelCorresponding author.; Institute of Applied Physics, The Hebrew University of Jerusalem, Jerusalem 9190401, IsraelWe introduce a physics-based computational reconstruction framework for non-invasive photoacoustic tomography through a thick aberrating layer. Our wave-based approach leverages an analytic formulation of diffraction to beamform a photoacoustic image, when the aberrating layer profile is known. When the profile of the aberrating layer is unknown, the same analytical formulation serves as the basis for an automatic-differentiation regularized optimization algorithm that simultaneously reconstructs both the profile of the aberrating layer and the optically absorbing targets. Results from numerical studies and proof-of-concept experiments show promise for fast beamforming that takes into account diffraction effects occurring in the propagation through thick, highly-aberrating layers.http://www.sciencedirect.com/science/article/pii/S2213597924000016Photoacoustic tomographyAberration correctionModel-based reconstructionBeamformingIterative optimization
spellingShingle Yevgeny Slobodkin
Ori Katz
Computational wave-based photoacoustic imaging through an unknown thick aberrating layer
Photoacoustics
Photoacoustic tomography
Aberration correction
Model-based reconstruction
Beamforming
Iterative optimization
title Computational wave-based photoacoustic imaging through an unknown thick aberrating layer
title_full Computational wave-based photoacoustic imaging through an unknown thick aberrating layer
title_fullStr Computational wave-based photoacoustic imaging through an unknown thick aberrating layer
title_full_unstemmed Computational wave-based photoacoustic imaging through an unknown thick aberrating layer
title_short Computational wave-based photoacoustic imaging through an unknown thick aberrating layer
title_sort computational wave based photoacoustic imaging through an unknown thick aberrating layer
topic Photoacoustic tomography
Aberration correction
Model-based reconstruction
Beamforming
Iterative optimization
url http://www.sciencedirect.com/science/article/pii/S2213597924000016
work_keys_str_mv AT yevgenyslobodkin computationalwavebasedphotoacousticimagingthroughanunknownthickaberratinglayer
AT orikatz computationalwavebasedphotoacousticimagingthroughanunknownthickaberratinglayer