Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles

Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles

Abstract The prevalence of neurological/neurodegenerative diseases, such as Alzheimer's disease is known to be increasing due to an aging population and is anticipated to further grow in the decades ahead. The treatment of brain diseases is challenging partly due to the inaccessibility of thera...

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Main Authors: Yamir Islam, Andrew G. Leach, Jayden Smith, Stefano Pluchino, Christopher R. Coxon, Muttuswamy Sivakumaran, James Downing, Amos A. Fatokun, Meritxell Teixidò, Touraj Ehtezazi
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Advanced Science
Subjects:
aging brain
blood–brain barrier model
complement activation
drug delivery to the brain
immunogenicity
nanoparticles
Online Access:https://doi.org/10.1002/advs.202002085

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