The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model

The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model

Combination therapy for Buruli ulcer (BU) is suboptimal. Here, Liu et al. show that the candidate drug TB47 has potent bactericidal activity against Mycobacterium ulcerans in vitro and in a mouse model, which underscores its potential for shortening the course of BU and treating other mycobacterial...

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Bibliographic Details
Main Authors: Yang Liu, Yamin Gao, Jianxiong Liu, Yaoju Tan, Zhiyong Liu, Chiranjibi Chhotaray, Huofeng Jiang, Zhili Lu, Gift Chiwala, Shuai Wang, Gaelle Makafe, Md Mahmudul Islam, H. M. Adnan Hameed, Xingshan Cai, Changwei Wang, Xinjie Li, Shouyong Tan, Tianyu Zhang
Format: Article
Language:English
Published: Nature Portfolio 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08464-y

Internet

https://doi.org/10.1038/s41467-019-08464-y

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