Self-Assembly of Amyloid Fibrils into 3D Gel Clusters versus 2D Sheets

Self-Assembly of Amyloid Fibrils into 3D Gel Clusters versus 2D Sheets

The deposition of dense fibril plaques represents the pathological hallmark for a multitude of human disorders, including many neurodegenerative diseases. Fibril plaques are predominately composed of amyloid fibrils, characterized by their underlying cross beta-sheet architecture. Research into the...

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Bibliographic Details
Main Authors: Kanchana Karunarathne, Nabila Bushra, Olivia Williams, Imad Raza, Laura Tirado, Diane Fakhre, Fadia Fakhre, Martin Muschol
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomolecules
Subjects:
hen egg-white lysozyme
amyloid fibril
self-assembly
gelation
plaque formation
Online Access:https://www.mdpi.com/2218-273X/13/2/230

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