Peripheral and central capillary non-perfusion in diabetic retinopathy: An updated overview
Capillary non-perfusion (CNP) is one of the key hallmarks of diabetic retinopathy (DR), which may develop both in the periphery and at the posterior pole. Our perspectives on CNP have extended with the introduction of optical coherence tomography angiography (OCTA) and ultra-widefield imaging, and t...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1125062/full |
| _version_ | 1797862092631441408 |
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| author | Alessio Antropoli Alessandro Arrigo Lamberto La Franca Lorenzo Bianco Eugenio Barlocci Emanuele Fusi Francesco Bandello Maurizio Battaglia Parodi |
| author_facet | Alessio Antropoli Alessandro Arrigo Lamberto La Franca Lorenzo Bianco Eugenio Barlocci Emanuele Fusi Francesco Bandello Maurizio Battaglia Parodi |
| author_sort | Alessio Antropoli |
| collection | DOAJ |
| description | Capillary non-perfusion (CNP) is one of the key hallmarks of diabetic retinopathy (DR), which may develop both in the periphery and at the posterior pole. Our perspectives on CNP have extended with the introduction of optical coherence tomography angiography (OCTA) and ultra-widefield imaging, and the clinical consequences of peripheral and macular CNP have been well characterized. Fluorescein angiography (FA) continues to be the gold standard for detecting and measuring CNP, particularly when ultra-widefield imaging is available. OCTA, on the other hand, is a quicker, non-invasive approach that allows for a three-dimensional examination of CNP and may soon be regarded as an useful alternative to FA. In this review, we provide an updated scenario regarding the characteristics, clinical impact, and management of central and peripheral CNP in DR. |
| first_indexed | 2024-04-09T22:13:43Z |
| format | Article |
| id | doaj.art-3eb621320a714d4e883ca53480c421c1 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-09T22:13:43Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-3eb621320a714d4e883ca53480c421c12023-03-23T04:54:08ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-03-011010.3389/fmed.2023.11250621125062Peripheral and central capillary non-perfusion in diabetic retinopathy: An updated overviewAlessio AntropoliAlessandro ArrigoLamberto La FrancaLorenzo BiancoEugenio BarlocciEmanuele FusiFrancesco BandelloMaurizio Battaglia ParodiCapillary non-perfusion (CNP) is one of the key hallmarks of diabetic retinopathy (DR), which may develop both in the periphery and at the posterior pole. Our perspectives on CNP have extended with the introduction of optical coherence tomography angiography (OCTA) and ultra-widefield imaging, and the clinical consequences of peripheral and macular CNP have been well characterized. Fluorescein angiography (FA) continues to be the gold standard for detecting and measuring CNP, particularly when ultra-widefield imaging is available. OCTA, on the other hand, is a quicker, non-invasive approach that allows for a three-dimensional examination of CNP and may soon be regarded as an useful alternative to FA. In this review, we provide an updated scenario regarding the characteristics, clinical impact, and management of central and peripheral CNP in DR.https://www.frontiersin.org/articles/10.3389/fmed.2023.1125062/fullperipheral capillary non-perfusiondiabetic macular ischemiadiabetic retinopathyfluorescein angiography (FA)optical coherence tomography angiography (OCTA) |
| spellingShingle | Alessio Antropoli Alessandro Arrigo Lamberto La Franca Lorenzo Bianco Eugenio Barlocci Emanuele Fusi Francesco Bandello Maurizio Battaglia Parodi Peripheral and central capillary non-perfusion in diabetic retinopathy: An updated overview Frontiers in Medicine peripheral capillary non-perfusion diabetic macular ischemia diabetic retinopathy fluorescein angiography (FA) optical coherence tomography angiography (OCTA) |
| title | Peripheral and central capillary non-perfusion in diabetic retinopathy: An updated overview |
| title_full | Peripheral and central capillary non-perfusion in diabetic retinopathy: An updated overview |
| title_fullStr | Peripheral and central capillary non-perfusion in diabetic retinopathy: An updated overview |
| title_full_unstemmed | Peripheral and central capillary non-perfusion in diabetic retinopathy: An updated overview |
| title_short | Peripheral and central capillary non-perfusion in diabetic retinopathy: An updated overview |
| title_sort | peripheral and central capillary non perfusion in diabetic retinopathy an updated overview |
| topic | peripheral capillary non-perfusion diabetic macular ischemia diabetic retinopathy fluorescein angiography (FA) optical coherence tomography angiography (OCTA) |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1125062/full |
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