Association Between Blood Lead Level With High Blood Pressure in US (NHANES 1999–2018)

BackgroundLead is a toxic metal for human health, but the effect on blood pressure (BP) is still controversial. The object of this study was to demonstrate the association between blood lead levels with BP and hypertension (HTN).MethodsWe used the database from the National Health and Nutrition Exam...

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Main Author: Ziyao Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2022.836357/full
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author Ziyao Huang
author_facet Ziyao Huang
author_sort Ziyao Huang
collection DOAJ
description BackgroundLead is a toxic metal for human health, but the effect on blood pressure (BP) is still controversial. The object of this study was to demonstrate the association between blood lead levels with BP and hypertension (HTN).MethodsWe used the database from the National Health and Nutrition Examination Survey (NHANES, 1999–2018) to perform a cross-sectional study. We performed multivariate regressions to examine the association between blood lead level with HTN and BP, and then a subgroup analysis was performed.ResultsA total of 32,289 participants were included in this study, but no significant difference was found between blood lead levels and HTN. However, the association between blood lead levels with systolic and diastolic pressure became positive. In the subgroup analysis stratified by race, the association between non-Hispanic white and black people still existed.ConclusionThe association between blood lead levels with HTN was not significant, but it was positively associated with BP. Besides, the association between non-Hispanic white and black people was also significant.
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spelling doaj.art-3eb7bb7825fa4edaba3bfa21eb907b0d2022-12-22T01:53:22ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-04-011010.3389/fpubh.2022.836357836357Association Between Blood Lead Level With High Blood Pressure in US (NHANES 1999–2018)Ziyao HuangBackgroundLead is a toxic metal for human health, but the effect on blood pressure (BP) is still controversial. The object of this study was to demonstrate the association between blood lead levels with BP and hypertension (HTN).MethodsWe used the database from the National Health and Nutrition Examination Survey (NHANES, 1999–2018) to perform a cross-sectional study. We performed multivariate regressions to examine the association between blood lead level with HTN and BP, and then a subgroup analysis was performed.ResultsA total of 32,289 participants were included in this study, but no significant difference was found between blood lead levels and HTN. However, the association between blood lead levels with systolic and diastolic pressure became positive. In the subgroup analysis stratified by race, the association between non-Hispanic white and black people still existed.ConclusionThe association between blood lead levels with HTN was not significant, but it was positively associated with BP. Besides, the association between non-Hispanic white and black people was also significant.https://www.frontiersin.org/articles/10.3389/fpubh.2022.836357/fullblood lead level (BLL)blood pressurehypertensionNHANES (National Health and Nutrition Examination Survey)high blood pressure (HBP)
spellingShingle Ziyao Huang
Association Between Blood Lead Level With High Blood Pressure in US (NHANES 1999–2018)
Frontiers in Public Health
blood lead level (BLL)
blood pressure
hypertension
NHANES (National Health and Nutrition Examination Survey)
high blood pressure (HBP)
title Association Between Blood Lead Level With High Blood Pressure in US (NHANES 1999–2018)
title_full Association Between Blood Lead Level With High Blood Pressure in US (NHANES 1999–2018)
title_fullStr Association Between Blood Lead Level With High Blood Pressure in US (NHANES 1999–2018)
title_full_unstemmed Association Between Blood Lead Level With High Blood Pressure in US (NHANES 1999–2018)
title_short Association Between Blood Lead Level With High Blood Pressure in US (NHANES 1999–2018)
title_sort association between blood lead level with high blood pressure in us nhanes 1999 2018
topic blood lead level (BLL)
blood pressure
hypertension
NHANES (National Health and Nutrition Examination Survey)
high blood pressure (HBP)
url https://www.frontiersin.org/articles/10.3389/fpubh.2022.836357/full
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