Recurrent diabetic myonecrosis in an African American woman with long-standing uncontrolled type 2 diabetes: a case report

Abstract Background Diabetic myonecrosis, also called diabetic muscle infarction, is an uncommon complication of uncontrolled diabetes mellitus and is frequently underdiagnosed. The objective of this case report is to highlight the challenges in the early diagnosis and treatment of this disease. Cas...

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Main Authors: Varsha Kurup, Ying Nagoshi, Marie Rivera-Zengotita, Edlira Maska
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Medical Case Reports
Subjects:
Online Access:https://doi.org/10.1186/s13256-023-03896-z
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author Varsha Kurup
Ying Nagoshi
Marie Rivera-Zengotita
Edlira Maska
author_facet Varsha Kurup
Ying Nagoshi
Marie Rivera-Zengotita
Edlira Maska
author_sort Varsha Kurup
collection DOAJ
description Abstract Background Diabetic myonecrosis, also called diabetic muscle infarction, is an uncommon complication of uncontrolled diabetes mellitus and is frequently underdiagnosed. The objective of this case report is to highlight the challenges in the early diagnosis and treatment of this disease. Case presentation A 51-year-old African American woman with a long history of uncontrolled diabetes mellitus presented to her primary care physician with right thigh pain. A diagnosis of diabetes myonecrosis was made on the basis of magnetic resonance imaging, biopsy, and negative autoimmune panel. After failing conservative treatment, the patient was treated with prednisone with gradual improvement of her symptoms. However, she had a recurrence of myonecrosis almost one year after her original presentation, which was also treated with prednisone. The recurrence had a shorter course and the patient recovered well. Challenges to the treatment in this patient were her debilitating pain and her underlying chronic kidney disease. Conclusions A high index of suspicion for diabetic myonecrosis is necessary when a patient with diabetes presents with unilateral focal leg pain and swelling. Magnetic resonance imaging and biopsy can help confirm the diagnosis. Prednisone may be considered in patients who lack spontaneous regression with just rest. Educating healthcare professionals about this uncommon condition is of utmost importance in avoiding unnecessary testing and inappropriate treatment.
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spelling doaj.art-3eb85fe2b2134b808e207cec4b004cf82023-08-06T11:15:43ZengBMCJournal of Medical Case Reports1752-19472023-06-011711510.1186/s13256-023-03896-zRecurrent diabetic myonecrosis in an African American woman with long-standing uncontrolled type 2 diabetes: a case reportVarsha Kurup0Ying Nagoshi1Marie Rivera-Zengotita2Edlira Maska3Division of General Internal Medicine, Department of Internal Medicine, University of Florida College of MedicineDivision of General Internal Medicine, Department of Internal Medicine, University of Florida College of MedicineDepartment of Radiology, University of Florida College of MedicineDivision of General Internal Medicine, Department of Internal Medicine, University of Florida College of MedicineAbstract Background Diabetic myonecrosis, also called diabetic muscle infarction, is an uncommon complication of uncontrolled diabetes mellitus and is frequently underdiagnosed. The objective of this case report is to highlight the challenges in the early diagnosis and treatment of this disease. Case presentation A 51-year-old African American woman with a long history of uncontrolled diabetes mellitus presented to her primary care physician with right thigh pain. A diagnosis of diabetes myonecrosis was made on the basis of magnetic resonance imaging, biopsy, and negative autoimmune panel. After failing conservative treatment, the patient was treated with prednisone with gradual improvement of her symptoms. However, she had a recurrence of myonecrosis almost one year after her original presentation, which was also treated with prednisone. The recurrence had a shorter course and the patient recovered well. Challenges to the treatment in this patient were her debilitating pain and her underlying chronic kidney disease. Conclusions A high index of suspicion for diabetic myonecrosis is necessary when a patient with diabetes presents with unilateral focal leg pain and swelling. Magnetic resonance imaging and biopsy can help confirm the diagnosis. Prednisone may be considered in patients who lack spontaneous regression with just rest. Educating healthcare professionals about this uncommon condition is of utmost importance in avoiding unnecessary testing and inappropriate treatment.https://doi.org/10.1186/s13256-023-03896-zDiabetes mellitusRecurrent diabetic myonecrosisAsymmetric leg swellingDiabetic muscle infarctionCase report
spellingShingle Varsha Kurup
Ying Nagoshi
Marie Rivera-Zengotita
Edlira Maska
Recurrent diabetic myonecrosis in an African American woman with long-standing uncontrolled type 2 diabetes: a case report
Journal of Medical Case Reports
Diabetes mellitus
Recurrent diabetic myonecrosis
Asymmetric leg swelling
Diabetic muscle infarction
Case report
title Recurrent diabetic myonecrosis in an African American woman with long-standing uncontrolled type 2 diabetes: a case report
title_full Recurrent diabetic myonecrosis in an African American woman with long-standing uncontrolled type 2 diabetes: a case report
title_fullStr Recurrent diabetic myonecrosis in an African American woman with long-standing uncontrolled type 2 diabetes: a case report
title_full_unstemmed Recurrent diabetic myonecrosis in an African American woman with long-standing uncontrolled type 2 diabetes: a case report
title_short Recurrent diabetic myonecrosis in an African American woman with long-standing uncontrolled type 2 diabetes: a case report
title_sort recurrent diabetic myonecrosis in an african american woman with long standing uncontrolled type 2 diabetes a case report
topic Diabetes mellitus
Recurrent diabetic myonecrosis
Asymmetric leg swelling
Diabetic muscle infarction
Case report
url https://doi.org/10.1186/s13256-023-03896-z
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