Response variance in functional maps: neural darwinism revisited.
The mechanisms by which functional maps and map plasticity contribute to cortical computation remain controversial. Recent studies have revisited the theory of neural Darwinism to interpret the learning-induced map plasticity and neuronal heterogeneity observed in the cortex. Here, we hypothesize th...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3708906?pdf=render |
| _version_ | 1819268335951413248 |
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| author | Hirokazu Takahashi Ryo Yokota Ryohei Kanzaki |
| author_facet | Hirokazu Takahashi Ryo Yokota Ryohei Kanzaki |
| author_sort | Hirokazu Takahashi |
| collection | DOAJ |
| description | The mechanisms by which functional maps and map plasticity contribute to cortical computation remain controversial. Recent studies have revisited the theory of neural Darwinism to interpret the learning-induced map plasticity and neuronal heterogeneity observed in the cortex. Here, we hypothesize that the Darwinian principle provides a substrate to explain the relationship between neuron heterogeneity and cortical functional maps. We demonstrate in the rat auditory cortex that the degree of response variance is closely correlated with the size of its representational area. Further, we show that the response variance within a given population is altered through training. These results suggest that larger representational areas may help to accommodate heterogeneous populations of neurons. Thus, functional maps and map plasticity are likely to play essential roles in Darwinian computation, serving as effective, but not absolutely necessary, structures to generate diverse response properties within a neural population. |
| first_indexed | 2024-12-23T21:31:26Z |
| format | Article |
| id | doaj.art-3eb87abeed8041da82c1c093a7cfb698 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-23T21:31:26Z |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-3eb87abeed8041da82c1c093a7cfb6982022-12-21T17:30:27ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0187e6870510.1371/journal.pone.0068705Response variance in functional maps: neural darwinism revisited.Hirokazu TakahashiRyo YokotaRyohei KanzakiThe mechanisms by which functional maps and map plasticity contribute to cortical computation remain controversial. Recent studies have revisited the theory of neural Darwinism to interpret the learning-induced map plasticity and neuronal heterogeneity observed in the cortex. Here, we hypothesize that the Darwinian principle provides a substrate to explain the relationship between neuron heterogeneity and cortical functional maps. We demonstrate in the rat auditory cortex that the degree of response variance is closely correlated with the size of its representational area. Further, we show that the response variance within a given population is altered through training. These results suggest that larger representational areas may help to accommodate heterogeneous populations of neurons. Thus, functional maps and map plasticity are likely to play essential roles in Darwinian computation, serving as effective, but not absolutely necessary, structures to generate diverse response properties within a neural population.http://europepmc.org/articles/PMC3708906?pdf=render |
| spellingShingle | Hirokazu Takahashi Ryo Yokota Ryohei Kanzaki Response variance in functional maps: neural darwinism revisited. PLoS ONE |
| title | Response variance in functional maps: neural darwinism revisited. |
| title_full | Response variance in functional maps: neural darwinism revisited. |
| title_fullStr | Response variance in functional maps: neural darwinism revisited. |
| title_full_unstemmed | Response variance in functional maps: neural darwinism revisited. |
| title_short | Response variance in functional maps: neural darwinism revisited. |
| title_sort | response variance in functional maps neural darwinism revisited |
| url | http://europepmc.org/articles/PMC3708906?pdf=render |
| work_keys_str_mv | AT hirokazutakahashi responsevarianceinfunctionalmapsneuraldarwinismrevisited AT ryoyokota responsevarianceinfunctionalmapsneuraldarwinismrevisited AT ryoheikanzaki responsevarianceinfunctionalmapsneuraldarwinismrevisited |