De novo biosynthesis of antiarrhythmic alkaloid ajmaline

Abstract The antiarrhythmic drug ajmaline is a monoterpenoid indole alkaloid (MIA) isolated from the Ayurvedic plant Rauvolfia serpentina (Indian Snakeroot). Research into the biosynthesis of ajmaline and another renowned MIA chemotherapeutic drug vinblastine has yielded pivotal advancements in the...

Полное описание

Библиографические подробности
Главные авторы: Jun Guo, Di Gao, Jiazhang Lian, Yang Qu
Формат: Статья
Язык:English
Опубликовано: Nature Portfolio 2024-01-01
Серии:Nature Communications
Online-ссылка:https://doi.org/10.1038/s41467-024-44797-z

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