Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview

Lipomatous neoplasms are a rare entity in the pediatric population, comprising less than 10% of soft tissue tumors in the first two decades of life. Some characteristics of pediatric adipocytic tumors are analogous to their adult counterparts, some pediatric lipomatous lesions however harbor unique...

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Main Authors: Eline Ameloot, Fleur Cordier, Jo Van Dorpe, David Creytens
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/7/1938
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author Eline Ameloot
Fleur Cordier
Jo Van Dorpe
David Creytens
author_facet Eline Ameloot
Fleur Cordier
Jo Van Dorpe
David Creytens
author_sort Eline Ameloot
collection DOAJ
description Lipomatous neoplasms are a rare entity in the pediatric population, comprising less than 10% of soft tissue tumors in the first two decades of life. Some characteristics of pediatric adipocytic tumors are analogous to their adult counterparts, some pediatric lipomatous lesions however harbor unique features. In recent years, there have been significant advances in the understanding of the pathogenesis and hence in the classification and treatment of pediatric adipocytic tumors. This literature-based article will provide a review of the presently known clinicopathological, immunohistochemical and molecular features of pediatric lipomatous lesions.
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spelling doaj.art-3ebf177d3d024920a907ebfdcffbde8a2023-11-30T23:28:56ZengMDPI AGJournal of Clinical Medicine2077-03832022-03-01117193810.3390/jcm11071938Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular OverviewEline Ameloot0Fleur Cordier1Jo Van Dorpe2David Creytens3Department of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, BelgiumDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, BelgiumDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, BelgiumDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, BelgiumLipomatous neoplasms are a rare entity in the pediatric population, comprising less than 10% of soft tissue tumors in the first two decades of life. Some characteristics of pediatric adipocytic tumors are analogous to their adult counterparts, some pediatric lipomatous lesions however harbor unique features. In recent years, there have been significant advances in the understanding of the pathogenesis and hence in the classification and treatment of pediatric adipocytic tumors. This literature-based article will provide a review of the presently known clinicopathological, immunohistochemical and molecular features of pediatric lipomatous lesions.https://www.mdpi.com/2077-0383/11/7/1938adipocyticlipoblastomalipoblastomatosislipomatosisliposarcomapediatric
spellingShingle Eline Ameloot
Fleur Cordier
Jo Van Dorpe
David Creytens
Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview
Journal of Clinical Medicine
adipocytic
lipoblastoma
lipoblastomatosis
lipomatosis
liposarcoma
pediatric
title Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview
title_full Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview
title_fullStr Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview
title_full_unstemmed Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview
title_short Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview
title_sort update of pediatric lipomatous lesions a clinicopathological immunohistochemical and molecular overview
topic adipocytic
lipoblastoma
lipoblastomatosis
lipomatosis
liposarcoma
pediatric
url https://www.mdpi.com/2077-0383/11/7/1938
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AT davidcreytens updateofpediatriclipomatouslesionsaclinicopathologicalimmunohistochemicalandmolecularoverview