Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview
Lipomatous neoplasms are a rare entity in the pediatric population, comprising less than 10% of soft tissue tumors in the first two decades of life. Some characteristics of pediatric adipocytic tumors are analogous to their adult counterparts, some pediatric lipomatous lesions however harbor unique...
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Format: | Article |
Language: | English |
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MDPI AG
2022-03-01
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Series: | Journal of Clinical Medicine |
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Online Access: | https://www.mdpi.com/2077-0383/11/7/1938 |
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author | Eline Ameloot Fleur Cordier Jo Van Dorpe David Creytens |
author_facet | Eline Ameloot Fleur Cordier Jo Van Dorpe David Creytens |
author_sort | Eline Ameloot |
collection | DOAJ |
description | Lipomatous neoplasms are a rare entity in the pediatric population, comprising less than 10% of soft tissue tumors in the first two decades of life. Some characteristics of pediatric adipocytic tumors are analogous to their adult counterparts, some pediatric lipomatous lesions however harbor unique features. In recent years, there have been significant advances in the understanding of the pathogenesis and hence in the classification and treatment of pediatric adipocytic tumors. This literature-based article will provide a review of the presently known clinicopathological, immunohistochemical and molecular features of pediatric lipomatous lesions. |
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format | Article |
id | doaj.art-3ebf177d3d024920a907ebfdcffbde8a |
institution | Directory Open Access Journal |
issn | 2077-0383 |
language | English |
last_indexed | 2024-03-09T11:42:20Z |
publishDate | 2022-03-01 |
publisher | MDPI AG |
record_format | Article |
series | Journal of Clinical Medicine |
spelling | doaj.art-3ebf177d3d024920a907ebfdcffbde8a2023-11-30T23:28:56ZengMDPI AGJournal of Clinical Medicine2077-03832022-03-01117193810.3390/jcm11071938Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular OverviewEline Ameloot0Fleur Cordier1Jo Van Dorpe2David Creytens3Department of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, BelgiumDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, BelgiumDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, BelgiumDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, BelgiumLipomatous neoplasms are a rare entity in the pediatric population, comprising less than 10% of soft tissue tumors in the first two decades of life. Some characteristics of pediatric adipocytic tumors are analogous to their adult counterparts, some pediatric lipomatous lesions however harbor unique features. In recent years, there have been significant advances in the understanding of the pathogenesis and hence in the classification and treatment of pediatric adipocytic tumors. This literature-based article will provide a review of the presently known clinicopathological, immunohistochemical and molecular features of pediatric lipomatous lesions.https://www.mdpi.com/2077-0383/11/7/1938adipocyticlipoblastomalipoblastomatosislipomatosisliposarcomapediatric |
spellingShingle | Eline Ameloot Fleur Cordier Jo Van Dorpe David Creytens Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview Journal of Clinical Medicine adipocytic lipoblastoma lipoblastomatosis lipomatosis liposarcoma pediatric |
title | Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview |
title_full | Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview |
title_fullStr | Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview |
title_full_unstemmed | Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview |
title_short | Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview |
title_sort | update of pediatric lipomatous lesions a clinicopathological immunohistochemical and molecular overview |
topic | adipocytic lipoblastoma lipoblastomatosis lipomatosis liposarcoma pediatric |
url | https://www.mdpi.com/2077-0383/11/7/1938 |
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