Platelet Bone Morphogenetic Protein-4 Mediates Vascular Inflammation and Neointima Formation after Arterial Injury

Platelet Bone Morphogenetic Protein-4 Mediates Vascular Inflammation and Neointima Formation after Arterial Injury

The purpose of this study is to investigate the role of platelet bone morphogenetic proteins (BMP)-4 during vascular inflammation and remodeling in a mouse model of carotid wire injury. Transgenic mice with a platelet-specific deletion of BMP-4 (<i>BMP4<sup>Plt−/−</sup></i>)...

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Bibliographic Details
Main Authors: Marietta Jank, Nikolaus von Niessen, Christoph B. Olivier, Hannah Schmitt, Nathaly Anto-Michel, Ingo Hilgendorf, Christoph Bode, Martin Moser, Jennifer S. Esser, Qian Zhou
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
BMP
platelet
restenosis
inflammation
Online Access:https://www.mdpi.com/2073-4409/10/8/2027

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